Q5R7W2
Gene name |
SLC25A3 (PHC) |
Protein name |
Phosphate carrier protein, mitochondrial |
Names |
Phosphate transport protein, PTP, Solute carrier family 25 member 3 |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100173229 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5R7W2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5R7W2-F1 | Predicted | AlphaFoldDB |
No variants for Q5R7W2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5R7W2 | |||||
No associated diseases with Q5R7W2
3 regional properties for Q5R7W2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Mitochondrial substrate/solute carrier | 62 - 149 | IPR018108-1 |
| repeat | Mitochondrial substrate/solute carrier | 159 - 246 | IPR018108-2 |
| repeat | Mitochondrial substrate/solute carrier | 260 - 339 | IPR018108-3 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| inorganic phosphate transmembrane transporter activity | Enables the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. |
| symporter activity | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial phosphate ion transmembrane transport | The process in which a phosphate ion is transported across a mitochondrial membrane, into or out of the mitochondrion. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFSSVAHLAR | ANPFNTPHLQ | LVHDGLGDFR | SRPPGPTGQP | RRPRNLAAAA | VEEYSCEFGS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AKYYALCGFG | GVLSCGLTHT | AVVPLDLVKC | RMQVDPQKYK | GIFNGFSVTL | KEDGVRGLAK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GWAPTFLGYS | MQGLCKFGFY | EVFKVLYSNM | LGEENTYLWR | TSLYLAASAS | AEFFADIALA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PMEAAKVRIQ | TQPGYANTLR | DAAPKMYKEE | GLKAFYKGVA | PLWMRQIPYT | MMKFACFERT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VEALYKFVVP | KPRSECSKPE | QLVVTFVAGY | IAGVFCAIVS | HPADSVVSVL | NKEKGSSASL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VLKRLGFKGV | WKGLFARIIM | IGTLTALQWF | IYDSVKVYFR | LPRPPPPEMP | ESLKKKLGLT |
| Q |