Q5R6T6

PR
Gene name
WDR91
Protein name
WD repeat-containing protein 91
Names
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100174638
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

213-295 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5R6T6

Entry ID Method Resolution Chain Position Source
AF-Q5R6T6-F1 Predicted AlphaFoldDB

No variants for Q5R6T6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5R6T6

No associated diseases with Q5R6T6

4 regional properties for Q5R6T6

Type Name Position InterPro Accession
repeat WD40 repeat 357 - 401 IPR001680-1
repeat WD40 repeat 406 - 444 IPR001680-2
repeat WD40 repeat 516 - 606 IPR001680-3
repeat WD40 repeat 665 - 706 IPR001680-4

Functions

Description
EC Number
Subcellular Localization
  • Early endosome membrane ; Peripheral membrane protein
  • Late endosome membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
early endosome membrane The lipid bilayer surrounding an early endosome.
extrinsic component of endosome membrane The component of an endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
late endosome membrane The lipid bilayer surrounding a late endosome.

1 GO annotations of molecular function

Name Definition
phosphatidylinositol 3-kinase regulator activity Modulates the activity of any of the phosphatidylinositol 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates.

2 GO annotations of biological process

Name Definition
early endosome to late endosome transport The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
regulation of phosphatidylinositol 3-kinase activity Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an inositol lipid at the 3' position of the inositol ring.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIFHCEVDKI VDQLQQLMQV YDLAALRDYW SYLERRLFSR LEDIYRPTIH KLKTSLFRFY
70 80 90 100 110 120
LVYTIQTNRN DKAQEFFAKQ ATELQNQAEW KDWFVLPFLP SPDTNPTFAT YFSRQWADTF
130 140 150 160 170 180
IVSLHNFLSV LFQCMPVPVI LNFDAECRRT NQVQEENEVL RQKLFALQAE IHRLKKEEQQ
190 200 210 220 230 240
PEEEEALVQH KLPPYVSNMD RLGDSELAMV CSQRNASLSQ SPRVGFLSSL LPQSKKSPSR
250 260 270 280 290 300
LSPAQGPPQA QSSAKKESFG GQGTKGKDPT SGAKDGKGLL SGLATGESGW SQHRQRRLQD
310 320 330 340 350 360
HGKERKELFS TTTSQCAEKK PEASGPEAEP CPELHTEPVE PLTRTSLAGP EGGGVRPEQP
370 380 390 400 410 420
FIVLGQEEYG EHHSSIMHCR VDCSGRRVAS LDVDGVIKVW SFNPIMQTKA SSISKSPLLS
430 440 450 460 470 480
LEWATKRDRL LLLGSGVGTV RLYDTEAKKN LCEININDDM PRILSLACSP NGASFVCSAA
490 500 510 520 530 540
APSLTSQVDF SAPDIGSKGM NQVPGRLLLW DTKTMKQQLQ FSLDPEPIAI NCTAFNHNGN
550 560 570 580 590 600
LLVTGAADGV IRLFDMQQHE CAMSWRAHYG EVYSVEFSYD ENTVYSIGED GKFIQWNIHK
610 620 630 640 650 660
SGLKVSEYSL PSDATGPFVL SGYSGYKQVQ VPRGRLFAFD SEGNYMLTCS ATGGVIYKLG
670 680 690 700 710
GDEKVLESCL SLGGHRAPVV TVDWSTAMDC GTCLTASMDG KIKLTTLLAH KA