Q5R6F6
Gene name |
MTMR7 |
Protein name |
Myotubularin-related protein 7 |
Names |
Inositol 1,3-bisphosphate phosphatase, Phosphatidylinositol-3-phosphate phosphatase |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100173546 |
EC number |
3.1.3.64: Phosphoric monoester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5R6F6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5R6F6-F1 | Predicted | AlphaFoldDB |
No variants for Q5R6F6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5R6F6 | |||||
No associated diseases with Q5R6F6
1 regional properties for Q5R6F6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | 60S ribosomal protein L10P, insertion domain | 125 - 194 | IPR040637 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.3.64 | Phosphoric monoester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| endomembrane system | A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| inositol bisphosphate phosphatase activity | Catalysis of the reaction: myo-inositol bisphosphate + H2O = myo-inositol phosphate + phosphate. |
| phosphatidylinositol-3,5-bisphosphate phosphatase activity | Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate. |
| phosphatidylinositol-3-phosphatase activity | Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| phosphatidylinositol biosynthetic process | The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. |
| phosphatidylinositol dephosphorylation | The process of removing one or more phosphate groups from a phosphatidylinositol. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEHIRTPKVE | NVRLVDRVSP | KKAALGTLYL | TATHVIFVEN | SPGSRKETWI | LHSQISTIEK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QATTATGCPL | LIRCKNFQII | QLIIPQERDC | HDVYISLIRL | ARPVKYGELY | CFSFNPMLDK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EEREQGWVLI | DLSEEYKRMG | LPNHYWQLSD | VNRDYRVCDS | YPTELYVPKS | ATAHIIVGSS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KFRSRRRFPV | LSYYYKDNHA | SICRSSQPLS | GFSARCLEDE | QMLQAIRKAN | PGSDFVYVVD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TRPKLNAMAN | RAAGKGYENE | DNYSNIKFQF | IGIENIHVMR | NSLQKMLEVC | ELKSPSMSDF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LWGLENSGWL | RHIKAIMDAG | IFIAKAVSEE | GTSVLVHCSD | GWDRTAQVCS | VASLLLDPHY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RTLKGFMVLI | EKDWISFGHK | FNHRYGNLDG | DPKEISPVID | QFIECVWQLM | EQFPCAFEFN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ERFLIHIQHH | IYSCQFGNFL | CNSQKERQEL | KIQERTYSLW | AHLWKNRADY | LNPLFRADHS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QTQGTLHLPT | IPCNFMYKFW | SGMYNRFEKG | MQPRQSVTDY | LMAVKEETQQ | LEEELEALEE |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RLEKIQKVQL | NCTKVKSKQS | EPSKHSGFST | SDNSIANTPQ | DYSGNMKSFP | SRSPSQGDED |
| 610 | 620 | 630 | 640 | 650 | |
| SALILTQDNL | KSSDPDLSAN | SDQESGVEDL | SCRSPSGGEH | APSEDSGKDR | DSDEAVFLTA |