Q5R615
Gene name |
RAB33B |
Protein name |
Ras-related protein Rab-33B |
Names |
|
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100173632 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5R615
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5R615-F1 | Predicted | AlphaFoldDB |
No variants for Q5R615
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5R615 | |||||
No associated diseases with Q5R615
1 regional properties for Q5R615
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 33 - 181 | IPR005225 |
Functions
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi lumen | The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
9 GO annotations of biological process
| Name | Definition |
|---|---|
| autophagosome assembly | The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm. |
| intra-Golgi vesicle-mediated transport | The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network). |
| negative regulation of constitutive secretory pathway | Any process that stops, prevents or reduces the frequency, rate or extent of constitutive secretory pathway. |
| protein localization to Golgi apparatus | A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| Rab protein signal transduction | The series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state. |
| regulation of Golgi organization | Any process that modulates the frequency, rate or extent of Golgi organization. |
| regulation of retrograde vesicle-mediated transport, Golgi to ER | Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER. |
| skeletal system morphogenesis | The process in which the anatomical structures of the skeleton are generated and organized. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAEEMESSLE | ASFSSSGAVS | GASGFLPPAR | SRIFKIIVIG | DSNVGKTCLT | YRFCAGRFPD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RTEATIGVDF | RERAVEIDGE | RIKIQLWDTA | GQERFRKSMV | QHYYRNVHAV | VFVYDMTNMA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SFHSLPSWIE | ECKQHLLASD | IPRILVGNKC | DLRSAIQVPT | DLAQKFADTH | SMPLFETSAK |
| 190 | 200 | 210 | 220 | ||
| NPNDNDHVEA | IFMTLAHKLK | SHKPLMLSQP | PDNGIILKPE | PKPAMTCWC |