Q5R5W0
Gene name |
LASP1 |
Protein name |
LIM and SH3 domain protein 1 |
Names |
LASP-1 |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100173670 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5R5W0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5R5W0-F1 | Predicted | AlphaFoldDB |
No variants for Q5R5W0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5R5W0 | |||||
No associated diseases with Q5R5W0
1 regional properties for Q5R5W0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Amine oxidase | 23 - 460 | IPR002937 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cell cortex | The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. |
| cytoskeleton | A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. |
| focal adhesion | A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ). |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| actin filament binding | Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits. |
| metal ion binding | Binding to a metal ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| ion transport | The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNPNCARCGK | IVYPTEKVNC | LDKFWHKACF | HCETCKMTLN | MKNYKGYEKK | PYCNAHYPKQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SFTMVADTPE | NLRLKQQSEL | QSQVRYKEEF | EKNKGKGFSV | VADTPELQRI | KKTQDQISNI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KYHEEFEKSR | MGPSGGEGME | PERRDSQDSS | SYRRPLEQQQ | PHHIPTSAPV | YQQPQQQPVA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QSYGGYKEPA | APVSIQRSAP | GGGGKRYRAV | YDYSAADEDE | VSFQDGDTIV | NVQQIDDGWM |
| 250 | 260 | ||||
| YGTVERTGDT | GMLPANYVEA | I |