Q5R5M2

PR
Gene name
AP1G1
Protein name
AP-1 complex subunit gamma-1
Names
Adaptor protein complex AP-1 subunit gamma-1, Adaptor-related protein complex 1 subunit gamma-1, Clathrin assembly protein complex 1 gamma-1 large chain, Gamma-adaptin, Gamma1-adaptin, Golgi adaptor HA1/AP1 adaptin subunit gamma-1
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100173736
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

562-726 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5R5M2

Entry ID Method Resolution Chain Position Source
AF-Q5R5M2-F1 Predicted AlphaFoldDB

No variants for Q5R5M2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5R5M2

No associated diseases with Q5R5M2

3 regional properties for Q5R5M2

Type Name Position InterPro Accession
domain Oxoglutarate/iron-dependent dioxygenase 165 - 270 IPR005123
domain Non-haem dioxygenase N-terminal domain 14 - 91 IPR026992
domain Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain 173 - 267 IPR044861

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus
  • Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Cytoplasm, perinuclear region
  • Cytoplasmic vesicle, clathrin-coated vesicle
  • Membrane, clathrin-coated pit
  • Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex (By similarity)
  • Co-localizes with AFTPH/aftiphilin in the cytoplasm (By similarity)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
AP-1 adaptor complex A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).
perinuclear region of cytoplasm Cytoplasm situated near, or occurring around, the nucleus.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
vesicle-mediated transport A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPAPIRLREL IRTIRTARTQ AEEREMIQKE CAAIRSSFRE EDNTYRCRNV AKLLYMHMLG
70 80 90 100 110 120
YPAHFGQLEC LKLIASQKFT DKRIGYLGAM LLLDERQDVH LLMTNCIKND LNHSTQFVQG
130 140 150 160 170 180
LALCTLGCMG SSEMCRDLAG EVEKLLKTSN SYLRKKAALC AVHVIRKVPE LMEMFLPATK
190 200 210 220 230 240
NLLNEKNHGV LHTSVVLLTE MCERSPDMPA HFRKLVPQLV RILKNLIMSG YSPEHDVSGI
250 260 270 280 290 300
SDPFLQVRIL RLLRILGRND DDSSEAMNDI LAQVATNTET SKNVGNAILY ETVLTIMDIK
310 320 330 340 350 360
SESGLRVLAI NILGRFLLNN DKNIRYVALT SLLKTVRTDH NTVQRHRSTI VDCLKDLDVS
370 380 390 400 410 420
IKRRAMELSF ALVNGNNIRG MMKELLYFLD SCEPEFKADC ASGIFLAAEK YAPSKRWHID
430 440 450 460 470 480
TIMRVLTTAG SYVRDDAVPN LIQLITNSVE MHAYTVQRLY KAILGDYSQQ PLVQVAAWCI
490 500 510 520 530 540
GEYGDLLVSG QCEEEGPIQV TEDEVLDILE SVLISNMSTS VTRGYALTAI MKLSTRFTCT
550 560 570 580 590 600
VNRIKKVVSI YGSSIDVELQ QRAVEYNALF KKYDHMRSAL LERMPVMEKV TTNGPTEIVQ
610 620 630 640 650 660
TNGETEPAPL ETKPPPSGPQ PTSQANDLLD LLGGNDITPV IPTAPTSKPS SAGGELLDLL
670 680 690 700 710 720
GDINLTGAPA AAPAPASVPQ ISQPPFLLDG LSSQPLFNDI AAGIPSITAY SKNGLKIEFT
730 740 750 760 770 780
FERSNTNPSV TVITIQASNS TELDMTDFVF QAAVPKTFQL QLLSPSSSIV PAFNTGTITQ
790 800 810 820
VIKVLNPQKQ QLRMRIKLTY NHKGSAMQDL AEVNNFPPQS WQ