Q5R5G2

PR
Gene name
SEC23B
Protein name
Protein transport protein Sec23B
Names
SEC23-related protein B
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100173777
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

13-85 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5R5G2

Entry ID Method Resolution Chain Position Source
AF-Q5R5G2-F1 Predicted AlphaFoldDB

No variants for Q5R5G2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5R5G2

No associated diseases with Q5R5G2

6 regional properties for Q5R5G2

Type Name Position InterPro Accession
domain Zinc finger, Sec23/Sec24-type 58 - 98 IPR006895
domain Sec23/Sec24, trunk domain 127 - 392 IPR006896
domain Sec23/Sec24, helical domain 520 - 617 IPR006900
domain Gelsolin-like domain 633 - 719 IPR007123
domain Sec23/Sec24 beta-sandwich 403 - 506 IPR012990
domain Sec23, C-terminal 611 - 731 IPR037550

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm, cytosol
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
COPII vesicle coat One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.

1 GO annotations of molecular function

Name Definition
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
COPII-coated vesicle budding The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle.
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATYLEFIQQ NEERDGVRFS WNVWPSSRLE ATRMVVPLAC LLTPLKERPD LPPVQYEPVL
70 80 90 100 110 120
CSRPTCKAVL NPLCQVDYRA KLWACNFCFQ RNQFPPAYGG ISEVNQPAEL MPQFSTIEYV
130 140 150 160 170 180
IQRGAQSPLI FLYVVDTCLE EDDLQALKES LQMSLSLLPP DALVGLITFG RMVQVHELSC
190 200 210 220 230 240
EGISKSYVFR GTKDLTAKQI QDMLGLTKPA MPMQQARPAQ PQEHPFASSR FLQPVHKIDM
250 260 270 280 290 300
NLTDLLGELQ RDPWPVTQGK RPLRSTGVAL SIAVGLLEGT FPNTGARIML FTGGPPTQGP
310 320 330 340 350 360
GMVVGDELKI PIRSWHDIEK DNARFMKKAT KHYEMLANRT AANGHCIDIY ACALDQTGLL
370 380 390 400 410 420
EMKCCANLTG GYMVMGDSFN TSLFKQTFQR IFTKDFNGDF RMAFGATLDV KTSRELKIAG
430 440 450 460 470 480
AIGPCVSLNV KGPCVSENEL GVGGTSQWKI CGLDPTSTLG IYFEVVNQHN TPIPQGGRGA
490 500 510 520 530 540
IQFVTHYQHS STQRRIRVTT IARNWADVQS QLRHIEAAFD QEAAAVLMAR LGVFRAESEE
550 560 570 580 590 600
GPDVLRWLDR QLIRLCQKFG QYNKEDPTSF RLSDSFSLYP QFMFHLRRSP FLQVFNNSPD
610 620 630 640 650 660
SSYYRHHFAR QDLTQSLIMI QPILYSYSFH GPPEPVLLDS SSILADRILL MDTFFQIVIY
670 680 690 700 710 720
LGETIAQWRK AGYQDMPEYE NFKHLLQAPL DDAQEILQAR FPMPRYINTE HGGSQARFLL
730 740 750 760
SKVNPSQTHN NLYAWGQETG APILTDDVSL QVFMDHLKKL AVSSAC