Q5R5F0

PR
Gene name
LDHA
Protein name
L-lactate dehydrogenase A chain
Names
LDH-A, LDH muscle subunit, LDH-M
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100173786
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-45 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5R5F0

Entry ID Method Resolution Chain Position Source
AF-Q5R5F0-F1 Predicted AlphaFoldDB

No variants for Q5R5F0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5R5F0

No associated diseases with Q5R5F0

3 regional properties for Q5R5F0

Type Name Position InterPro Accession
domain Lactate/malate dehydrogenase, N-terminal 22 - 160 IPR001236
active_site L-lactate dehydrogenase, active site 190 - 196 IPR018177
domain Lactate/malate dehydrogenase, C-terminal 164 - 324 IPR022383

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
L-lactate dehydrogenase activity Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.

1 GO annotations of biological process

Name Definition
carboxylic acid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATLKDQLIH NLLKEEQTPQ NKITVVGVGA VGMACAISIL MKDLADELAL VDVIEDKLKG
70 80 90 100 110 120
EMMDLQHGSL FLRTPKIVSG KDYNVTANSK LVIITAGARQ QEGESRLNLV QRNVNIFKFI
130 140 150 160 170 180
IPNVVKYSPN CKLLIVSNPV DILTYVAWKI SGFPKNRVIG SGCNLDSARF RYLMGERLGV
190 200 210 220 230 240
HPSSCHGWVL GEHGDSSVPV WSGMNVAGVS LKTLHPDLGT DKDKEQWKEV HKQVVESAYE
250 260 270 280 290 300
VIKLKGYTSW AIGLSVADLA ESIMKNLRRV HPVSTMIKGL YGIKDDVFLS VPCILGQNGI
310 320 330
SDLVKVTLTS EEEARLKKSA DTLWGIQKEL QF