Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q5R539

Entry ID Method Resolution Chain Position Source
AF-Q5R539-F1 Predicted AlphaFoldDB

No variants for Q5R539

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5R539

No associated diseases with Q5R539

2 regional properties for Q5R539

Type Name Position InterPro Accession
domain SERRATE/Ars2, C-terminal 645 - 846 IPR007042
domain SERRATE/Ars2, N-terminal 153 - 262 IPR021933

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleoplasm
  • Cytoplasm
  • Predominantly nuclear
  • Shuttles between the nucleus and the cytoplasm in a CRM1-dependent way (By similarity)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

4 GO annotations of biological process

Name Definition
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
neuronal stem cell population maintenance Any process in by an organism or tissue maintains a population of neuronal stem cells.
primary miRNA processing A process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGDSDDEYDR RRRDKFRRER SDYDRSRERD ERRRGDDWND REWDHGRERR SRGEYRDYDR
70 80 90 100 110 120
NRRERFSPPR HELSPPQKRM RRDWDGHSSD PYHSGYEMPY AGGGGGPTYG PPQPWGHPGV
130 140 150 160 170 180
HIMQHHVLPI QARLGSIAEI DLGVPPPVMK TFKEFLLSLD DSVDETEAVK RYNDYKLDFR
190 200 210 220 230 240
RQQMQDFFLA HKDEEWFRSK YHPDEVGKRR QEARGALQNR LRVFLSLMET GWFDNLLLDI
250 260 270 280 290 300
DKADAIVKML DAAVIKMEGG TENDLRILEQ EEEEEQAGKP GEPGKKEEGR AGAGLGDGER
310 320 330 340 350 360
KTNDKDEKKE DSKQAENDSS NDDKTKKSEG DGDKEEKKED SEKEAKKSSK KRNRKHSGDD
370 380 390 400 410 420
SFDEGSMSES ESESESGQAE EEKEEAEALK EKEKPKEEEW EKPKDAAGLE CKPRPLHKTC
430 440 450 460 470 480
SLFMRNIAPN ISRAEIISLC KRYPGFMRVA LSEPQPERRF FRRGWVTFDR SVNIKEICWN
490 500 510 520 530 540
LQNIRLRECE LSPGVNRDLT RRVRNINGIT QHKQIVRNDI KLAAKLIHTL DDRTQLWASE
550 560 570 580 590 600
PGTPPLPTSL PSQNPILKNI TDYLIEEVSA EEEELLGSSG GAPPEEPPKE GNPAEINVER
610 620 630 640 650 660
DEKLIKVLDK LLLYLRIVHS LDYYNTCEYP NEDEMPNRCG IIHVRGPMPP NRISHGEVLE
670 680 690 700 710 720
WQKTFEEKLT PLLSVRESLS EEEAQKMGRK DPEQEVEKFV TSNTQELGKD KWLCPLSGKK
730 740 750 760 770 780
FKGPEFVRKH IFNKHAEKIE EVKKEVAFFN NFLTDAKRPA LPEIKPAQPP GPAQSLTPGL
790 800 810 820 830 840
PYPHQTPQGL MPYGQPRPPI LGYGAGAVRP AVPTGGPPYP HAPYGAGRGN YDAFRGQGGY
850 860 870
PGKPRNRMVR GDPRAIVEYR DLDAPDDVDF F