Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q5R4U3

Entry ID Method Resolution Chain Position Source
AF-Q5R4U3-F1 Predicted AlphaFoldDB

No variants for Q5R4U3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5R4U3

No associated diseases with Q5R4U3

4 regional properties for Q5R4U3

Type Name Position InterPro Accession
domain Calcium binding and coiled-coil domain-like 125 - 415 IPR012852
domain SKICH domain 17 - 120 IPR041611
domain CALCOCO1/2, zinc finger UBZ1-type 751 - 778 IPR041641-1
domain CALCOCO1/2, zinc finger UBZ1-type 778 - 805 IPR041641-2

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Mitochondrion
  • Preautophagosomal structure
  • Cytoplasmic vesicle, autophagosome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTSFQEVPLQ TSNFAHVIFQ NVAKSYLPNA HLECHYTLTP YIHPHPKDWV GIFKVGWSTA
70 80 90 100 110 120
RDYYTFLWSP MPEHYVEGST VNCVLAFQGY YLPNDDGEFY QFCYVTHKGE IRGASTPFQF
130 140 150 160 170 180
RASSPVEELL TMEDEGNSDM LVVTTKAGLL ELKIEKTMKE KEELLKLIAV LEKETAQLRE
190 200 210 220 230 240
QVGRMERELN HEKERCDQLQ AEQKGLTEVT QSLKMENEEF KKRFSDATSK AHQLEEDIVS
250 260 270 280 290 300
VTHKAIEKET ELDSLKDKLK KAQHEREQLE CQLKTEKDEK ELYKVHLKNT EIENTKLMSE
310 320 330 340 350 360
VQTLKNLDGN KESVITHFKE EIGRLQLCLA EKENLQRTFL LTTSSKEDTF FLKEQLRKAE
370 380 390 400 410 420
EQVQATRQEV VFLAKELSDA VNVRDRTMAD LHTARLENEK VKKQLADAVA ELKLNAMKKD
430 440 450 460 470 480
QDKTDTLEHE LRREVEDLKL RLQMAADHYK EKFKECQRLQ KQINKLSDQS ANNNNVFTKK
490 500 510 520 530 540
MGNQQKVNDA SVNTDPATSA STVDVKPSPS AAEADFDIVT KGQVCEMTKE IADKTEKYNK
550 560 570 580 590 600
CKQLLQDEKA KCNKYADELA KMELKWKEQV KIAENVKLEL AEVQDNYKLQ LAEKDKEISG
610 620 630 640 650 660
LTSHLENLSR EKELKRSLEN QAERKMEGQN SQSPQCLKTC SEQNGYVLTL SNAQPVLQYG
670 680 690 700 710 720
NPYASQETRD GADGAFYPDE IQRPPVRVPS WGLEDNVVCS QPARNLSRPD GLEDSEDSKE
730 740 750 760 770 780
DENAPTAPDP PSQHLRGHGT GFCFDSSFDV HKKCPLCELM FPPNYDQSKF EEHVESHWKV
790 800 810
CPMCSEQFPP DYDQQVFERH VQTHFDQNVL NFD