Q5R4T1

PR
Gene name
UBL4A
Protein name
Ubiquitin-like protein 4A
Names
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100173917
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

47-146 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5R4T1

Entry ID Method Resolution Chain Position Source
AF-Q5R4T1-F1 Predicted AlphaFoldDB

No variants for Q5R4T1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5R4T1

No associated diseases with Q5R4T1

7 regional properties for Q5R4T1

Type Name Position InterPro Accession
domain Ubiquitin-like domain 1 - 73 IPR000626
conserved_site Ubiquitin conserved site 27 - 52 IPR019954
domain Ubiquitin domain 11 - 31 IPR019956-1
domain Ubiquitin domain 32 - 52 IPR019956-2
domain Ubiquitin domain 53 - 74 IPR019956-3
domain Ubl4, C-terminal TUGS domain 96 - 142 IPR041421
domain UBL4A-like, ubiquitin-like domain 1 - 72 IPR044724

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytosol
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
BAT3 complex A protein complex found in mammals that transfers tail-anchored (TA) proteins from SGTA to GET3 (ASNA1/TRC4) for targeting to the endoplasmic reticulum membrane. Also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD). Consists of BAG6 (BAT3) and its cofactors GET4 (TRC35) and UBL4A.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
tail-anchored membrane protein insertion into ER membrane A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQLTVKALQG RECSLQVPED ELVSTLKQLV SEKLNVPVRQ QRLLFKGKAL ADGKRLSDYS
70 80 90 100 110 120
IGPNSKLNLV VKPLEKVLLE EGEAQRLADS PPPQVWQLIS KVLARHFSAA DASRVLEQPQ
130 140 150
RDYERSLSRL TLDDIERLAS RFLHPEVTET MEKGFSK