Q5R4S2
Gene name |
B4GAT1 |
Protein name |
Beta-1,4-glucuronyltransferase 1 |
Names |
I-beta-1,3-N-acetylglucosaminyltransferase, iGnT, N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase, Poly-N-acetyllactosamine extension enzyme, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100173924 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5R4S2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5R4S2-F1 | Predicted | AlphaFoldDB |
No variants for Q5R4S2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5R4S2 | |||||
No associated diseases with Q5R4S2
No regional properties for Q5R4S2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5R4S2 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| glucuronosyltransferase activity | Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside. |
| metal ion binding | Binding to a metal ion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| axon guidance | The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues. |
| protein O-linked mannosylation | The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQMSYAIRCA | FYQLLLAALM | LVAMLQLLYL | SLLSGLHGQE | EQDQYFEFFP | PSPRSVDQVK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TQLRTALASG | GVLDASGDYR | VYRGLLKTTM | DPNDVILATH | ASVDNLLHLS | GLLERWEGPL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SVSVFAATKE | EAQLATVLAY | ALSSHCPDMR | ARVAMHLVCP | SRYEAAVPDP | REPGEFALLR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SCQEVFDKLA | RVAQPGINYA | LGTNVSYPNN | LLRNLAREGA | NYALVIDVDM | VPSEGLWRGL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| REMLDQSNQW | GGTALVVPAF | EIRRARRMPM | NKNELVQLYQ | VGEVRPFYYG | LCTPCQAPTN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YSRWVNLPEE | SLLRPAYVVP | WQDPWEPFYV | AGGKVPTFDE | RFRQYGFNRI | SQACELHVAG |
| 370 | 380 | 390 | 400 | 410 | |
| FDFEVLNEGF | LVHKGFKEAL | KFHPQKEAEN | QHNKILYRQF | KQELKAKYPN | SPRRC |