Q5R111

PR
Gene name
rlmD
Protein name
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
Names
23S rRNA(m5U1939)-methyltransferase
Species
Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
KEGG Pathway
ilo:IL0805
EC number
2.1.1.190: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-53 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5R111

Entry ID Method Resolution Chain Position Source
AF-Q5R111-F1 Predicted AlphaFoldDB

No variants for Q5R111

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5R111

No associated diseases with Q5R111

2 regional properties for Q5R111

Type Name Position InterPro Accession
active_site RNA methyltransferase TrmA, active site 372 - 406 IPR030390
conserved_site RNA methyltransferase TrmA, conserved site 431 - 441 IPR030391

Functions

Description
EC Number 2.1.1.190 Methyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
iron ion binding Binding to an iron (Fe) ion.
RNA binding Binding to an RNA molecule or a portion thereof.
rRNA (uridine-C5-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAQFFKPQKR NKSVSKTLKG QVSALDHQAR AVVRAAVKGQ STRFIMGALP GEVIEYKTAG
70 80 90 100 110 120
KHSGHLERIL EPSSDRREVP CEYYASCGGC DFQHIDEQKQ LAHKRQVVEE LFQKFGVFNP
130 140 150 160 170 180
QTSSLPWQEP LVSEPMRYRR RVRLATRWLG KEQKLLIGFR EAQSHHIVPI EDCLVADEIL
190 200 210 220 230 240
LHCVNTLYPL LNTSTVASKL GHIEAINTNT PVILLRITEA LPGDAMQALQ EWQTVNKTNI
250 260 270 280 290 300
WLQSENDLQP LAGAAMPFDT SIDGDKLYFQ PGDFLQVNGG INQRMVQQAM DWLKPEKTQR
310 320 330 340 350 360
VYDFFAGIGN FSLPLARRAQ SVLAVEGVYR MAEQTRINAE SNGMDNLSSL SADLNEITAS
370 380 390 400 410 420
DLGKPADLWC LDPARPGAEG VVKLLHKLKP EHRPQRILYV SCAPDTLARD IAGMLTESKG
430 440
CNYRIIGLST VDMFPQTHHI ETMVCLERAS