Q5QU19

PR
Gene name
IL0724
Protein name
Putative pterin-4-alpha-carbinolamine dehydratase
Names
PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD
Species
Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
KEGG Pathway
ilo:IL0724
EC number
4.2.1.96: Hydro-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-56 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5QU19

Entry ID Method Resolution Chain Position Source
AF-Q5QU19-F1 Predicted AlphaFoldDB

No variants for Q5QU19

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5QU19

No associated diseases with Q5QU19

No regional properties for Q5QU19

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5QU19

Functions

Description
EC Number 4.2.1.96 Hydro-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
4-alpha-hydroxytetrahydrobiopterin dehydratase activity Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O.

1 GO annotations of biological process

Name Definition
tetrahydrobiopterin biosynthetic process The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSNLENARCE ACHADAPQVS DEELKELMRE IPDWTPVTND NVMMLQREFK FKNFKQALAF
70 80 90 100 110
TNRVGDLAEE EKHHPELVTE WGKVTVTWWT HAINGLHKND FIMAAKTDSV VDA