AiPD: Autoinhibited Protein Database

Gene name	Cep112 (Ccdc46)
Protein name	Centrosomal protein of 112 kDa
Names	Cep112, Coiled-coil domain-containing protein 46
Species	Mus musculus (Mouse)
KEGG Pathway	mmu:76380
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

135-204 (Predicted disordered autoinhibitory region) PR

135-204 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q5PR68-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs3389199572	9	K>N	No	EVA
rs3389216124	85	H>N	No	EVA
rs3402868124	115	S>N	No	EVA
rs3389213377	118	K>M	No	EVA
rs3402944514	119	L>*	No	EVA
rs3402656455	126	E>D	No	EVA
rs212469528	223	K>R	No	EVA
rs29483657	227	V>I	No	EVA
rs3389182603	228	S>F	No	EVA
rs3389210271	275	Q>H	No	EVA
rs3389226801	276	Q>*	No	EVA
rs3389205783	332	K>N	No	EVA
rs3389214582	339	L>M	No	EVA
rs3402135720	361	A>D	No	EVA
rs1131802649	373	Q>L	No	EVA
rs3389199595	380	I>M	No	EVA
rs13481220	507	E>G	No	EVA
rs3389205803	656	Y>F	No	EVA
rs3389216144	681	E>D	No	EVA
rs3389210292	682	K>M	No	EVA
rs220076536	690	D>G	No	EVA
rs3389205834	707	H>Q	No	EVA
rs3389226799	712	Q>R	No	EVA
rs235956354	834	S>N	No	EVA
rs3389216179	847	D>G	No	EVA
rs3389216179	847	D>V	No	EVA
rs3389214611	878	S>Y	No	EVA
rs250616920	879	H>N	No	EVA
rs3389225041	944	Q>H	No	EVA

Type	Name	Position	InterPro Accession
domain	Domain of unknown function DUF4485	13 - 98	IPR027831

		Description
EC Number
Subcellular Localization	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome	Localizes around spindle poles in some cells
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
centrosome	A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
inhibitory synapse	A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Name	Definition
No GO annotations for molecular function

Name	Definition
receptor localization to synapse	Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins