Q5P9Q9

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Anaplasma marginale (strain St Maries)
KEGG Pathway
ama:AM1120
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

491-600 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5P9Q9

Entry ID Method Resolution Chain Position Source
AF-Q5P9Q9-F1 Predicted AlphaFoldDB

No variants for Q5P9Q9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5P9Q9

No associated diseases with Q5P9Q9

9 regional properties for Q5P9Q9

Type Name Position InterPro Accession
domain Helicase, C-terminal 425 - 629 IPR001650
conserved_site SEC-C motif 851 - 868 IPR004027
domain SecA DEAD-like, N-terminal 5 - 390 IPR011115
domain SecA Wing/Scaffold 611 - 822 IPR011116
domain SecA, preprotein cross-linking domain 228 - 346 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 89 - 227 IPR014001
domain SecA motor DEAD 3 - 613 IPR014018
conserved_site SecA conserved site 488 - 503 IPR020937
domain SecA, C-terminal helicase domain 408 - 583 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLSMAKRVFW PYGYGSGRAS FHKIVKNINA MEEGLSALSD SELFSKTSHF KELLASGQTL
70 80 90 100 110 120
DDLLVPAFAV VRETARRVLN MRHFDVQLIG GIALHRCMIA EMKTGEGKTL VATLAAYLGA
130 140 150 160 170 180
LEGAGVHVVT VNDYLARRDS EWMGNIYQAL GMSVGCITGS SSDEQRKAAY ACDVLYSTNN
190 200 210 220 230 240
ELGFDYLRDN MKFGRESMVQ RGFNYAIVDE VDSILIDEAR TPLIISGPVE RDSALYGRVD
250 260 270 280 290 300
SLVRALTPED YEVEEKNRSA FLTEEGAVKV EKMLLSMGLI PVGSSLYDTE NIVMMHYVSQ
310 320 330 340 350 360
ALRAHKLFAV DKDYIVKNGN VVIIDEFTGR MMEGRRYSDG LHQALEAKER LTVNSENQTL
370 380 390 400 410 420
ASTTFQNYFR MYRRISGMTG TAATEADEFL GTYNLQAMQI PTNVPVRRVD MDDDVYCTEE
430 440 450 460 470 480
EKFEAVIDFI VECNKRLQPT LVGTISIEKS ELLSEMLTKR GIKHSVLNAR YHEKEAYIIA
490 500 510 520 530 540
QAGRPGAVTI ATNMAGRGTD IQLGGNPEML AKDELSGITS DEERSAKYEQ LVAQTKRDRD
550 560 570 580 590 600
VVVAAGGLCI VGTERHESRR IDNQLRGRSG RQGDPGLSKF FLSLEDDLLR IFGSDKVKGM
610 620 630 640 650 660
LKKLGMKRGE AIQHKWISKA IERAQKKVEA RNYDIRKSLL RFDDVINEQR QVVFEQRNQV
670 680 690 700 710 720
LDNDTYDFAF MYHSVNQDLV SRVVKDKYYD PSPETCEPLL SEVKRIYGVE LEPEKLQNLE
730 740 750 760 770 780
TKEQVVGYLD SFAQELLEKK AAEFVHNGEN LWDFAARRVL ITSLDHMWIE HLSALDSLKC
790 800 810 820 830 840
GINLRSIGQK DPLNEFKIEA FTMLKHMLLK FHEMVIQKLS SMRLERDASP ATQHMFRAAR
850 860 870
GGDSPFSGIS RNEKCPCGSG KKFKHCHGIL QL