Q5NZS1

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Aromatoleum aromaticum (strain EbN1) (Azoarcus sp (strain EbN1))
KEGG Pathway
eba:ebA5841
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

33-380 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5NZS1

Entry ID Method Resolution Chain Position Source
AF-Q5NZS1-F1 Predicted AlphaFoldDB

No variants for Q5NZS1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5NZS1

No associated diseases with Q5NZS1

7 regional properties for Q5NZS1

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 445 - 614 IPR000795
domain Small GTP-binding protein domain 449 - 604 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 368 - 419 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 60 - 98 IPR013575
domain Translation initiation factor IF- 2, domain 3 721 - 835 IPR023115
domain Translation initiation factor IF-2, domain II 620 - 714 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEQMSVTQFA GELKMPASVL LEQLQKAGVE KTGADQLLTE QDKARLLEYL RRSHGQSQPK
70 80 90 100 110 120
GKITLTRKQT SEIRATDSSG RARTVQVEVR KKRVFMKRDE VSAETGSLES AQIEEETAGL
130 140 150 160 170 180
PMGEIEPTPE PENIVEPVAE AIPEPEPVRE PEPEPEPIVE PEPEPEPEPE PEPQPEPEPR
190 200 210 220 230 240
PEPEPATVES GAPAKPEAPV RAPSRPPLRV SILSDEERAA REREARRHQE LRARQAADLK
250 260 270 280 290 300
AKQDREAAAR AAAEARRAEE EARVRAEAER RAEAAKPQPK EAAKAPAGTL HRPAKTEEKP
310 320 330 340 350 360
AGKDAKRTAR GDTAGESAKR RGLKTRGEVG ATTGSWRGAR GGGRRGAQDE HKSFQAPTEP
370 380 390 400 410 420
VVREIHVPET ISVADLAHKM SVKAAEVIKI LMKMGSMVTI NQVLDQETAM ILVEEMGHKA
430 440 450 460 470 480
FAAKLDDPDT YLESAEAHHD AAVEPRAPVV TVMGHVDHGK TSLLDYIRRA KVASGEAGGI
490 500 510 520 530 540
TQHIGAYHVE TPRGMLTFLD TPGHEAFTAM RARGAKATDI VILVVAADDG VMPQTREAIH
550 560 570 580 590 600
HAKAANVPLV VAVNKIDKPD ANPDRVKQEL VAEGVLPEEY GGDVMFINVS AKTGVGIDSL
610 620 630 640 650 660
LEAVLLQAEV LELTAPVDSP AKGLIIEARL DKGRGPVASL LVLSGTLRKG DVMLVGATFG
670 680 690 700 710 720
RIRAMLDENG KAIDHAGPSI PVEVLGLSDV PAAGDEAIAL ADEKKAREIA LFRQGKYREV
730 740 750 760 770 780
KLAKQQAAKL ESMFEQMAEG EVKTLPLIIK ADVQGSQEAL VQALNKLSTD EVRVNAIHSA
790 800 810 820 830 840
VGAISESDVN LAQASGAVII GFNTRADAGA RKLAETFGVD IRYYNIIYDA VDEVKAALSG
850 860 870 880 890 900
MLAPERRENV IGLVEVRQVF KVPKVGTVAG CYVLEGVVKR GSQVRVLRNH VVIHNGELES
910 920 930 940
LKRFKDDVKE VKFGFECGLS IRNFNDVQEG DQLEVFEIQE IARTL