Q5NZG2
Gene name |
lpxB |
Protein name |
Lipid-A-disaccharide synthase |
Names |
|
Species |
Aromatoleum aromaticum (strain EbN1) (Azoarcus sp (strain EbN1)) |
KEGG Pathway |
eba:ebA6002 |
EC number |
2.4.1.182: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5NZG2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5NZG2-F1 | Predicted | AlphaFoldDB |
No variants for Q5NZG2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5NZG2 | |||||
No associated diseases with Q5NZG2
No regional properties for Q5NZG2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5NZG2 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.182 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| lipid-A-disaccharide synthase activity | Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + H(+) + UDP. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| lipid A biosynthetic process | The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATRIAMVAG | EASGDLLASH | LIRAIRQQVP | EAEFYGIGGP | KMQAEGFDAL | WPCERLAVHG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YVDALKRYRE | LSGIRKALLR | RVQADRPDAF | IGVDAPDFNL | WLEGRIRSSG | IPAIHFVSPS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IWAWRGGRIK | GIARSVSHML | CLFPFEPALY | EKAGIPVSYV | GHPLADVFPL | VPDRAAAREL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LSLPTDCRIV | ALLPGSRQSE | VRSLAATYIE | TARLLAERHP | DIGFVVPLAT | RETRALFEQA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LHAADADELP | IRLLFGHAVE | AMTAADVVLV | ASGTASLEAA | LLKRPMVISY | RIGKWQYRLM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KRMAYLPWVG | LPNILCNDSV | VPELLQDDAT | PQALADALDR | WLNDADACAE | LALRFDALHR |
| 370 | 380 | 390 | |||
| ELRQDTAGRA | AAAILPYLNR | SPEWKPSRQS | A |