Q5NVS6

PR
Gene name
APOOL (FAM121A, MIC27)
Protein name
MICOS complex subunit MIC27
Names
Apolipoprotein O-like, Protein FAM121A
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100174091
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-86 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5NVS6

Entry ID Method Resolution Chain Position Source
AF-Q5NVS6-F1 Predicted AlphaFoldDB

No variants for Q5NVS6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5NVS6

No associated diseases with Q5NVS6

2 regional properties for Q5NVS6

Type Name Position InterPro Accession
domain Peptidase S9, prolyl oligopeptidase, catalytic domain 491 - 702 IPR001375
repeat WD40-like beta propeller 292 - 308 IPR011659

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Multi-pass membrane protein
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
MICOS complex Mitochondrial inner membrane complex involved in maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. In Saccharomyces cerevisiae the complex has six subunits: MIC10, MIC12, MIC19, MIC26, MIC27, and MIC60.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
cristae formation The assembly of cristae, the inwards folds of the inner mitochondrial membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAAIRMGKLT TMPAGLIYAS VSVHAAKEEE SKKQLVKPEQ LPIYTAPPLQ SKYVEEQPGH
70 80 90 100 110 120
LQMGFASIRT ATGCYIGWCK GVYVFVKNGI MDTVQFGKDA YVYMKNPPRD FLPKMGVITV
130 140 150 160 170 180
SGLAGLVSAR KGSKFKKITY PLGLATLGAT VCYPVQSVII AKVTAKKIYA TSQQIFGAVK
190 200 210 220 230 240
SLWTKSSKEE SLPKPKEKTK LGSSSEIEVP AKTTHVLKHS VPLPTELSSE AKTKSESTSD
250 260
VQISEVGGKI IGTWGPNVTN SGVLRI