Q5NVE1

PR
Gene name
AASDHPPT
Protein name
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
Names
4'-phosphopantetheinyl transferase, Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase, AASD-PPT
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100174162
EC number
2.7.8.7: Transferases for other substituted phosphate groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

216-303 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5NVE1

Entry ID Method Resolution Chain Position Source
AF-Q5NVE1-F1 Predicted AlphaFoldDB

No variants for Q5NVE1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5NVE1

No associated diseases with Q5NVE1

2 regional properties for Q5NVE1

Type Name Position InterPro Accession
domain ABC1 atypical kinase-like domain 93 - 344 IPR004147
domain UbiB domain, bacteria 93 - 344 IPR045308

Functions

Description
EC Number 2.7.8.7 Transferases for other substituted phosphate groups
Subcellular Localization
  • Cytoplasm, cytosol
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

2 GO annotations of molecular function

Name Definition
holo-[acyl-carrier-protein] synthase activity Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.
magnesium ion binding Binding to a magnesium (Mg) ion.

1 GO annotations of biological process

Name Definition
protein maturation Any process leading to the attainment of the full functional capacity of a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVFPAKRFCL VPSMEGVRWA FSCGTWLPSR AEWLLAVRSI QPEEKERIGQ FVFARDAKAA
70 80 90 100 110 120
MAGRLMIRKL VAEKLNIPWN HIRLQRTAKG KPVLAKDSSN PYPNFNFNIS HQGDYAVLAA
130 140 150 160 170 180
EPELQVGIDI MKTSFPGRGS IPEFFHIMKR KFTNKEWETI RGFKDEWTQL DMFYRNWALK
190 200 210 220 230 240
ESFIKAIGVG LGFELQRLEF DLSPLNLDIG QVYKETRLFL DGEEEKEWAF EESKIDEHHF
250 260 270 280 290 300
VAVALRKPDG SRHQDVPSQD DSKPTQRQFT ILNFNDLISS AVPMTPEDPS FWDCFCFTEE
IPIRNGTKS