Q5NL16

PR
Gene name
panB2
Protein name
3-methyl-2-oxobutanoate hydroxymethyltransferase 2
Names
Ketopantoate hydroxymethyltransferase 2, KPHMT 2
Species
Zymomonas mobilis subsp mobilis (strain ATCC 31821 / ZM4 / CP4)
KEGG Pathway
zmo:ZMO1970
EC number
2.1.2.11: Hydroxymethyl-, formyl- and related transferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-46 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5NL16

Entry ID Method Resolution Chain Position Source
AF-Q5NL16-F1 Predicted AlphaFoldDB

No variants for Q5NL16

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5NL16

No associated diseases with Q5NL16

No regional properties for Q5NL16

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5NL16

Functions

Description
EC Number 2.1.2.11 Hydroxymethyl-, formyl- and related transferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
3-methyl-2-oxobutanoate hydroxymethyltransferase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
pantothenate biosynthetic process The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSAIPSSNKR RTIPELRARK GKSPIVALTA YSALTARFVD PYADFILVGD SLAMVEHGMA
70 80 90 100 110 120
TTIGASLDMM ILHGQSVMRG SEKAAVVIDM PFGSYEASPQ EAYHNAVRIL SETGCSAVKL
130 140 150 160 170 180
EGGSHLAPVI AFLTARGVPV MGHIGLTPQY VQTLGGFKIQ GHSSEQQDKI KQDALDFEAA
190 200 210 220 230 240
GAFSVVLEGV TEPLAREITD NIAIPTIGIG ASSYCDGQVL VLEDMLGFND KVPRFVKKFA
250 260 270
HLGDDIKKAV SDYATAVSNR SFPAEDNIYR PKS