Q5ND52
Gene name |
Mrm3 |
Protein name |
rRNA methyltransferase 3, mitochondrial |
Names |
16S rRNA (guanosine(1370)-2'-O)-methyltransferase, 16S rRNA [Gm1370] 2'-O-methyltransferase, RNA methyltransferase-like protein 1 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:67390 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5ND52
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5ND52-F1 | Predicted | AlphaFoldDB |
27 variants for Q5ND52
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs226482872 | 4 | P>L | No | EVA | |
| rs226482872 | 4 | P>R | No | EVA | |
| rs3402222514 | 14 | S>T | No | EVA | |
| rs48464917 | 102 | R>K | No | EVA | |
| rs28199827 | 112 | K>R | No | EVA | |
| rs223904078 | 171 | E>G | No | EVA | |
| rs3389190647 | 201 | E>K | No | EVA | |
| rs1134161872 | 202 | T>P | No | EVA | |
| rs13459131 | 203 | P>L | No | EVA | |
| rs13459131 | 203 | P>Q | No | EVA | |
| rs3410610850 | 207 | T>I | No | EVA | |
| rs3389185720 | 212 | L>F | No | EVA | |
| rs3389144281 | 250 | P>L | No | EVA | |
| rs3389152098 | 257 | M>L | No | EVA | |
| rs3389190624 | 268 | N>K | No | EVA | |
| rs3402561716 | 298 | M>I | No | EVA | |
| rs3402451527 | 298 | M>T | No | EVA | |
| rs3389190666 | 301 | K>N | No | EVA | |
| rs3389193669 | 319 | Y>C | No | EVA | |
| rs3401852517 | 324 | D>N | No | EVA | |
| rs28199800 | 329 | K>R | No | EVA | |
| rs28199799 | 336 | E>D | No | EVA | |
| rs219306737 | 346 | G>E | No | EVA | |
| rs28199797 | 380 | V>I | No | EVA | |
| rs3389185691 | 385 | D>N | No | EVA | |
| rs3389193667 | 386 | S>G | No | EVA | |
| rs3389152091 | 416 | S>N | No | EVA |
No associated diseases with Q5ND52
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| identical protein binding | Binding to an identical protein or proteins. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| rRNA (guanosine-2'-O-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAPAKGMWC | SLGSLLRVVQ | TRDLNARRWV | RALRRSPVRV | LSPSGQVEER | KRAPDQQPRK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AVPKASSQGQ | RQKQPLETSP | SQTPHTWEEA | GLRYDKAFPG | DRRLSSVMTI | VKSRPFREKQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GKILLEGRRL | IADALKAGAV | PKAFFFSRLE | YVKELPVDKL | KDVSLIKVKF | EDIKDWSDLV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TPQGIMGIFA | KPDPVKMTYP | ETPLHHTLPL | VLICDNLRDP | GNLGTILRSA | AGAGCSKVLL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TKGCVDAWEP | KVLRAGMGAH | FQVPIVNNVE | WETVPNHLPP | DTRVYVADNC | GHYAQVQMSD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KTGDRDWACD | RRFLKFHKYE | EDLDTKTRKD | WLPKLEVQSY | DLDWTGAPAA | VVIGGETHGV |
| 370 | 380 | 390 | 400 | 410 | |
| SLESLQLAES | TGGKRLLIPV | VPGVDSLNSA | MAASILLFEG | KRQLRIKVED | LSRDRSYH |