Q5N8G1

PR
Gene name
ISPD (CMS)
Protein name
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic
Names
4-diphosphocytidyl-2C-methyl-D-erythritol synthase, OsCMS, MEP cytidylyltransferase
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:9266653
EC number
2.7.7.60: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-100 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5N8G1

Entry ID Method Resolution Chain Position Source
AF-Q5N8G1-F1 Predicted AlphaFoldDB

No variants for Q5N8G1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5N8G1

No associated diseases with Q5N8G1

1 regional properties for Q5N8G1

Type Name Position InterPro Accession
conserved_site 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site 171 - 178 IPR018294

Functions

Description
EC Number 2.7.7.60 Nucleotidyltransferases
Subcellular Localization
  • Plastid, chloroplast stroma
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
chloroplast stroma The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.

1 GO annotations of molecular function

Name Definition
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate.

1 GO annotations of biological process

Name Definition
isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MELRLCLRLH APPASAPTTH PPPPLSPSPN LALRRLRTGG SCAVAPRRHA RKWGSAVCAA
70 80 90 100 110 120
KADGAQGEAV KERSVSVVLL SGGQGKRMGA SMPKQYLPLL GLPIALHSLK TFCQLKEVKE
130 140 150 160 170 180
VVVVCDPDYK DIFEGSIENV QIPIKFALPG KERQDSVYNG LQEIDGDSEL VCVHDSARPL
190 200 210 220 230 240
VSSEDVKKVL EDAIVHGAAV LGVPVKATIK EADSNSFVVK TLDRKTLWEM QTPQVMRPSL
250 260 270 280 290
LRDGFELVKR DGLEVTDDVS IVEYLKHSVY ITEGSYTNIK VTTPDDLLLA ERLMNEK