Q5M870

PR
Gene name
Neurl3 (Lincr)
Protein name
E3 ubiquitin-protein ligase NEURL3
Names
Lung-inducible neuralized-related C3CH4 RING domain protein, Neuralized-like protein 3, RING-type E3 ubiquitin transferase NEURL3
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:316326
EC number
2.3.2.27: Aminoacyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-66 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5M870

Entry ID Method Resolution Chain Position Source
AF-Q5M870-F1 Predicted AlphaFoldDB

No variants for Q5M870

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5M870

No associated diseases with Q5M870

2 regional properties for Q5M870

Type Name Position InterPro Accession
domain Zinc finger, RING-type 197 - 236 IPR001841
domain Neuralized homology repeat (NHR) domain 15 - 174 IPR006573

Functions

Description
EC Number 2.3.2.27 Aminoacyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
ubiquitin protein ligase activity Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.

1 GO annotations of biological process

Name Definition
protein ubiquitination The process in which one or more ubiquitin groups are added to a protein.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9BR09 NEURL2 Neuralized-like protein 2 Homo sapiens (Human) PR
10 20 30 40 50 60
MGSRLSPEAN AEVPREALSF HGDATGAQVH LDDQRSTARR RSTFHDGIVF SQRPVWPGER
70 80 90 100 110 120
VALRVLRHED GWCGGLRVGF TRLDPAQVAA SCLPPFVCPD LEEQSPTWAA LLPEGFVRAG
130 140 150 160 170 180
NVVCFWVNRR GWLFAKVNAG RPLLLRKDVL VQGAPLWAVM DVYGTTKAIE LLDPKANAWI
190 200 210 220 230 240
TSGEPMPESE VTSGEECVIC FHNTANTRLM PCGHSQFCGS CAWHIFKDTA RCPMCRWQIE
250
EVAVEPSVKS GEGS