Q5M5S1

PR
Gene name
fabH
Protein name
Beta-ketoacyl-[acyl-carrier-protein] synthase III
Names
Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III
Species
Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
KEGG Pathway
stl:stu0382
EC number
2.3.1.180: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

152-231 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5M5S1

Entry ID Method Resolution Chain Position Source
AF-Q5M5S1-F1 Predicted AlphaFoldDB

No variants for Q5M5S1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5M5S1

No associated diseases with Q5M5S1

2 regional properties for Q5M5S1

Type Name Position InterPro Accession
domain Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal 237 - 320 IPR013747
domain Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal 106 - 183 IPR013751

Functions

Description
EC Number 2.3.1.180 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
3-oxoacyl-[acyl-carrier-protein] synthase activity Catalysis of the reaction: acyl-
beta-ketoacyl-acyl-carrier-protein synthase III activity Catalysis of the reaction: acetyl-CoA + malonyl-

1 GO annotations of biological process

Name Definition
fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAFAKISQVA HYAPAQVVTD DDLSKIMDTS DEWIRSRTGI QERRISLNEN TSDLATNVAY
70 80 90 100 110 120
QLLEKSGLSP EELDFVLVAT ISPDNSMPSV AARVQGTIGA VNAFAFDITA ACSGFVFALA
130 140 150 160 170 180
TAEKLIKSGA YKKGLVIGAE VLSKTLDWSD RATAVLFGDG AGGVLLEESE EEHFFGESLN
190 200 210 220 230 240
TDGSKGGLES GASAVISPYS DGTEQPNPYM QMDGKAIFDF AVKTVSKSIK ALVEEKGEPD
250 260 270 280 290 300
YFLLHQANIR ILDTMAKKID VSRDKFLANM MSYGNTSAAS IPILLSENVA NETLKLGSDQ
310
TILLSGFGGG LTWGSLIVKI