Q5KXU2

PR
Gene name
ndk
Protein name
Nucleoside diphosphate kinase
Names
NDK, NDP kinase, Nucleoside-2-P kinase
Species
Geobacillus kaustophilus (strain HTA426)
KEGG Pathway
gka:GK2209
EC number
2.7.4.6: Phosphotransferases with a phosphate group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

59-136 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5KXU2

Entry ID Method Resolution Chain Position Source
AF-Q5KXU2-F1 Predicted AlphaFoldDB

No variants for Q5KXU2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5KXU2

No associated diseases with Q5KXU2

2 regional properties for Q5KXU2

Type Name Position InterPro Accession
active_site Nucleoside diphosphate kinase, active site 113 - 121 IPR023005
domain Nucleoside diphosphate kinase-like domain 2 - 139 IPR034907

Functions

Description
EC Number 2.7.4.6 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
nucleoside diphosphate kinase activity Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.

4 GO annotations of biological process

Name Definition
CTP biosynthetic process The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate.
GTP biosynthetic process The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate.
nucleoside diphosphate phosphorylation The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside triphosphate.
UTP biosynthetic process The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAERTFIMVK PDGVQRNLIG EIVARFEKKG FQLVGAKLMQ VSRELAEQHY AEHKERPFFG
70 80 90 100 110 120
ELVDFITSGP VFAMVWEGEN VIAAARQMMG KTNPQEAAPG TIRGDFGLTV GKNVIHGSDS
130 140
PQSAKREISL FFKEEELVSY SKQINAWLY