Q5KXG9
Gene name |
namA |
Protein name |
NADPH dehydrogenase |
Names |
|
Species |
Geobacillus kaustophilus (strain HTA426) |
KEGG Pathway |
gka:GK2332 |
EC number |
1.6.99.1: With other acceptors |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for Q5KXG9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 3GR7 | X-ray | 230 A | A/B | 1-340 | PDB |
| 3GR8 | X-ray | 250 A | A/B | 1-340 | PDB |
| AF-Q5KXG9-F1 | Predicted | AlphaFoldDB |
No variants for Q5KXG9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5KXG9 | |||||
No associated diseases with Q5KXG9
1 regional properties for Q5KXG9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | NADH:flavin oxidoreductase/NADH oxidase, N-terminal | 5 - 322 | IPR001155 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.6.99.1 | With other acceptors |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| FMN binding | Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. |
| NADP binding | Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH. |
| NADPH dehydrogenase activity | Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor. |
| pentaerythritol trinitrate reductase activity | Catalysis of the reaction: pentaerythritol trinitrate + NADPH = NADP+ + nitrate + pentaerythritol dinitrate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| response to toxic substance | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNTMLFSPYT | IRGLTLKNRI | VMSPMCMYSC | DTKDGAVRTW | HKIHYPARAV | GQVGLIIVEA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TGVTPQGRIS | ERDLGIWSDD | HIAGLRELVG | LVKEHGAAIG | IQLAHAGRKS | QVPGEIIAPS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AVPFDDSSPT | PKEMTKADIE | ETVQAFQNGA | RRAKEAGFDV | IEIHAAHGYL | INEFLSPLSN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RRQDEYGGSP | ENRYRFLGEV | IDAVREVWDG | PLFVRISASD | YHPDGLTAKD | YVPYAKRMKE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QGVDLVDVSS | GAIVPARMNV | YPGYQVPFAE | LIRREADIPT | GAVGLITSGW | QAEEILQNGR |
| 310 | 320 | 330 | |||
| ADLVFLGREL | LRNPYWPYAA | ARELGAKISA | PVQYERGWRF |