Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q5K6N0

Entry ID Method Resolution Chain Position Source
AF-Q5K6N0-F1 Predicted AlphaFoldDB

42 variants for Q5K6N0

Variant ID(s) Position Change Description Diseaes Association Provenance
rs47886392 120 A>S No EVA
rs3389477131 140 E>D No EVA
rs3389469151 160 E>D No EVA
rs3389491161 169 L>S No EVA
rs3389435033 186 F>L No EVA
rs48884545 217 V>M No EVA
rs50343273 237 F>L No EVA
rs231630929 244 T>I No EVA
rs581567237 256 L>P No EVA
rs3389469156 260 G>V No EVA
rs51175013 263 V>I No EVA
rs3389482488 269 H>Y No EVA
rs107871252 273 A>T No EVA
rs3389442950 274 W>R No EVA
rs238303731 277 V>F No EVA
rs238303731 277 V>I No EVA
rs238303731 277 V>L No EVA
rs48853350 285 T>N No EVA
rs3389487861 296 T>K No EVA
rs3389454711 337 N>D No EVA
rs216012837 360 V>I No EVA
rs3389454718 361 F>I No EVA
rs3389425167 372 L>M No EVA
rs243277176 402 K>E No EVA
rs3389442962 423 S>P No EVA
rs225320097 431 K>N No EVA
rs3389467621 460 L>F No EVA
rs45670940 463 M>K No EVA
rs108289705 481 R>Q No EVA
rs3389475410 486 I>K No EVA
rs3412670728 516 G>W No EVA
rs3389482510 529 P>S No EVA
rs252747418 538 T>M No EVA
rs49652396 542 V>M No EVA
rs212750570 553 R>C No EVA
rs47821319 556 A>S No EVA
rs257636569 581 N>D No EVA
rs51866201 610 E>A No EVA
rs107917521 637 R>Q No EVA
rs262619114 657 S>P No EVA
rs3408218098 669 S>C No EVA
rs245668062 671 A>T No EVA

No associated diseases with Q5K6N0

No regional properties for Q5K6N0

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5K6N0

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
C9JQI7 TMEM232 Transmembrane protein 232 Homo sapiens (Human) PR
B1WBT0 Tmem232 Transmembrane protein 232 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MKAYKPPVVN KFGVISSTYH EELLKSIFES SNRRKSQKPK PSFSISKEFI LRFNHTDNPA
70 80 90 100 110 120
EEEELLEQAR RLIVRSKRKL GLKTLGSGKH VHLPTAWAEV IYLAQCKGEI QDEALNMLHA
130 140 150 160 170 180
SLDHVSFDHD QLPALFFLAE SVLYRLCCDA FMKGYLYSVE IKLVKIGYLI FLRLFVFFLH
190 200 210 220 230 240
GHLESFKQHL LRLQPYLYAL HFSEPSYYKY PNIISNVQFI LKTSEIICKR ELHSEPFVES
250 260 270 280 290 300
PDETEDPYSD LNHLQLNKRG YEVNHLLWHS VAAWSCVQNN RPQLTEVLEH LLFYKTQLQT
310 320 330 340 350 360
KCWLDSALAL MVLGEAAKLD MACLKTLMDL VTDFLENILS AQNQEENYNI YDTSWASEIV
370 380 390 400 410 420
FTYTTIIAEV CLYAATSDLR KTALIGFCAC KSPQQGISLT DKSEELPELD GASILTLLKY
430 440 450 460 470 480
FSSRISDNCE KVIWIGYYGI VYNLVKMSWE LQGEQDQDGL RNMIWQTLQK IKDYEQDPRI
490 500 510 520 530 540
RCALVIAQAE LNGPSDPFCT KATPNSGEEV FSKYIGWRIA TTLSRLFFPS LDVAPPKTPV
550 560 570 580 590 600
EVDLPRKHTI RERQPAKKRV LRFILKDHSS VVEVSMTPYP NFFTKADKKL EEIIDHHWQK
610 620 630 640 650 660
DMEARKREEE AYKAQNQKDK EEKEKIHFQE IMKQRERKLN KQTKPYEIIL SEKESGSEKK
670
CGFFELKPST APNAK