Q5JH35

PR
Gene name
rpl1
Protein name
50S ribosomal protein L1
Names
Species
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
KEGG Pathway
tko:TK1417
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-53 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5JH35

Entry ID Method Resolution Chain Position Source
AF-Q5JH35-F1 Predicted AlphaFoldDB

No variants for Q5JH35

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5JH35

No associated diseases with Q5JH35

3 regional properties for Q5JH35

Type Name Position InterPro Accession
domain RNA polymerase, subunit H/Rpb5 C-terminal 138 - 210 IPR000783
domain RNA polymerase, Rpb5, N-terminal 6 - 95 IPR005571
conserved_site RNA polymerase, subunit H/Rpb5, conserved site 143 - 156 IPR020608

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.

4 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
rRNA binding Binding to a ribosomal RNA.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.
tRNA binding Binding to a transfer RNA.

3 GO annotations of biological process

Name Definition
maturation of LSU-rRNA Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.
regulation of translation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAFDRQKLVE AVKEAKARAK PRNFTQTVEM AVNLKDVDLR KPENRFKLEV VLPHGRGKEP
70 80 90 100 110 120
KIAVIADGAV AEAAKKLGLD VISGEELEEL AKSPRQARKL AKKYDFFIAA APLMPKIGRY
130 140 150 160 170 180
LGRYLGPRNK MPVVVPPTMT NLEPIVEKLK KTVRIQLKNN PVVHAPIGTE DMDDEKLAEN
190 200 210
AEAVLNAIIN KLERGENQVK SVYIKTTMGP AVKVER