Q5JGR3

PR
Gene name
rpl7ae
Protein name
50S ribosomal protein L7Ae
Names
Ribosomal protein L8e
Species
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
KEGG Pathway
tko:TK1311
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-45 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

4 structures for Q5JGR3

Entry ID Method Resolution Chain Position Source
6SKF EM 295 A BH/BI 1-123 PDB
6SKG EM 265 A BH/BI 1-123 PDB
6TH6 EM 255 A BH/BI 1-123 PDB
AF-Q5JGR3-F1 Predicted AlphaFoldDB

No variants for Q5JGR3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5JGR3

No associated diseases with Q5JGR3

2 regional properties for Q5JGR3

Type Name Position InterPro Accession
conserved_site Ribosomal protein L7Ae conserved site 70 - 87 IPR004037
domain Ribosomal protein L7Ae/L30e/S12e/Gadd45 19 - 110 IPR004038

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.

4 GO annotations of molecular function

Name Definition
ribonuclease P activity Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor.
RNA binding Binding to an RNA molecule or a portion thereof.
rRNA binding Binding to a ribosomal RNA.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

3 GO annotations of biological process

Name Definition
maturation of LSU-rRNA Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
tRNA 5'-leader removal Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKPSYVKFE VPQELAEKAL EAVEIARDTG RIRKGTNETT KAVERGQAKL VIIAEDVDPE
70 80 90 100 110 120
EIVAHLPPLC EEKEIPYVYV PSKKELGAAA GLEVPAASVA IIEPGKAREL VEDIAMKVKE
LMK