Q5JFT4
Gene name |
aroC |
Protein name |
Chorismate synthase |
Names |
CS, 5-enolpyruvylshikimate-3-phosphate phospholyase |
Species |
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) |
KEGG Pathway |
tko:TK0262 |
EC number |
4.2.3.5: Acting on phosphates |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5JFT4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5JFT4-F1 | Predicted | AlphaFoldDB |
No variants for Q5JFT4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5JFT4 | |||||
No associated diseases with Q5JFT4
2 regional properties for Q5JFT4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Chorismate synthase, conserved site | 12 - 27 | IPR020541-1 |
| conserved_site | Chorismate synthase, conserved site | 120 - 136 | IPR020541-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.2.3.5 | Acting on phosphates |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| chorismate synthase activity | Catalysis of the reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. |
| FMN binding | Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| aromatic amino acid family biosynthetic process | The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). |
| cellular amino acid biosynthetic process | The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. |
| chorismate biosynthetic process | The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRGKLLSFSL | FGESHGKAVG | VLVEGLPPGI | EVSVEELKRE | LERRKGIERF | ATKRKETDEP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KILSGVFRGR | TTGTPVAVIV | ENRDVDSSYY | EEIRNTPRPG | HADYPAGIKY | FGYNDYRGGG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HFSGRLTVGV | VIAGYFAKKL | LEREGIKVRA | YLKRIGRVEA | HVSPEELLSS | ENPYCPDEGA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FEAMVEEMER | ARKAGDSVGG | IVEAVAFNVP | PGLGGPWEED | IEADIASALF | RIPAVKGVEF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GLGFGLAELR | GSQANDPFVL | KDGKVVTETN | NHGGVLGGMT | TGMPLVVRAA | FKPTPSIYLP |
| 310 | 320 | 330 | 340 | 350 | |
| QRTVDLGRME | EVTLKLRGRF | DSCIVPKALP | VVESSVAFVI | ADHLLRRRAW | EGMVR |