Q5JFT2

PR
Gene name
aroK
Protein name
Shikimate kinase
Names
SK
Species
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
KEGG Pathway
tko:TK0264
EC number
2.7.1.71: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

138-207 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5JFT2

Entry ID Method Resolution Chain Position Source
AF-Q5JFT2-F1 Predicted AlphaFoldDB

No variants for Q5JFT2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5JFT2

No associated diseases with Q5JFT2

1 regional properties for Q5JFT2

Type Name Position InterPro Accession
domain GHMP kinase N-terminal domain 76 - 143 IPR006204

Functions

Description
EC Number 2.7.1.71 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
shikimate kinase activity Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H(+).

4 GO annotations of biological process

Name Definition
aromatic amino acid family biosynthetic process The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
cellular amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
chorismate biosynthetic process The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRASASSAVT VVNAFATGVG SAIGIDLWTR AEVKLKGDGI EGEIRVRGEQ VRDFRLVKAV
70 80 90 100 110 120
ADVFREKTGE EFGIKFRIES EIPIAMGLKS SSAAANALSK ALADALGLDM SEMEVVKAGV
130 140 150 160 170 180
EAAKRAGVTL TGAFDDACAS YFGSLWVTDN LGMRVLHSSK VEPLPVVLLL PGKTLLTESL
190 200 210 220 230 240
GGRDFSPIRP YVEEAVRLAL EGEWRKAALI NGLVYSTYLG HPIEPFRIAL ERGAVVGLSG
250 260 270
KGPAVFAVTN EPEELAEEWE QFGKVLTTEL R