Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5IS98
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5IS98-F1 | Predicted | AlphaFoldDB |
No variants for Q5IS98
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5IS98 | |||||
No associated diseases with Q5IS98
1 regional properties for Q5IS98
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | RAI1-like | 224 - 295 | IPR013961 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| anchoring junction | A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| postsynaptic membrane | A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| G protein-coupled acetylcholine receptor activity | Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| gastric acid secretion | The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEGDSYGNAT | TINGTPVNHQ | PLERHRLWEV | ITIAAVTAVV | SLITIVGNVL | VMISFKVNSQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LKTVNNYYLL | SLACADLIIG | IFSMNLYTTY | ILMGRWALGS | LACDLWLALD | YVASNASVMN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LLVISFDRYF | SITRPLTYRA | KRTPKRAGIM | IGLAWLISFI | LWAPAILCWQ | YLVGKRTVPP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DECQIQFLSE | PTITFGTAIA | AFYIPVSVMT | ILYCRIYRET | EKRTKDLADL | QGSVSVTKAE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KRKPAHRALF | RSCFRCPRPT | LVQRERNQAS | RSSSHRSTSI | TGKPSQATGP | STNWAKAEEL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TTCSSYPSSE | DEDKPATDPV | LQVVYKSQGK | ESPGEEFSAE | EAEETFVKGQ | TDKNDCDSPD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YFLSPAAAHR | PKSQQCVAYK | FQLVVKADGT | QETNNGCHKV | KIMPCSFPVA | KEPSTKGLSP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NLSHQMTKRK | RMVLVKERKA | AQTLSAILLA | FIITWTPYNI | MVLVSTFCDK | CVPVALWHLG |
| 490 | 500 | 510 | 520 | 530 | |
| YWLCYVNSTV | NPICYALCNR | TFRKTFKMLL | LCQWKKKKVE | EKLYWQGNSK | LP |