Q5HPS2

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
KEGG Pathway
ser:SERP0836
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

4-158 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5HPS2

Entry ID Method Resolution Chain Position Source
AF-Q5HPS2-F1 Predicted AlphaFoldDB

No variants for Q5HPS2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5HPS2

No associated diseases with Q5HPS2

6 regional properties for Q5HPS2

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 222 - 391 IPR000795
domain Small GTP-binding protein domain 224 - 381 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 52 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 145 - 195 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 497 - 612 IPR023115
domain Translation initiation factor IF-2, domain II 398 - 492 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKKRIYEYA KELNLKSKEI IDELKSMNVE VSNHMQALEE EQIKALDKKF KASQAKDTNK
70 80 90 100 110 120
QNTQNNHQKS NNKQNSNDKE KQQSKNNSKP TKKKEQNNKG KQQNKNNKTN KNQKNNKNKK
130 140 150 160 170 180
NNKNNKPQNE VEETKEMPSK ITYQEGITVG ELAEKLNVES AGIIKKLFLL GIMANINQSL
190 200 210 220 230 240
DEETLELIAD DYGVEIEKEV VVDEEDLSIY FDDETDDSDA IERPAVVTIM GHVDHGKTTL
250 260 270 280 290 300
LDSIRNTKVT EGEAGGITQH IGAYQIENSG KKITFLDTPG HAAFTTMRAR GAQVTDITIL
310 320 330 340 350 360
VVAADDGVMP QTIEAINHAK EAEVPTIVAV NKIDKPTANP DRVMQELTEY GLIPEDWGGD
370 380 390 400 410 420
TIFVPLSALS GDGIDDLLEM IGLVAEVQEL KANPNKQAVG TVIEAELDKS RGPAASLLVQ
430 440 450 460 470 480
NGTLNVGDAI VVGNTYGRIR AMVNDLGKRI KSAGPSTPVE ITGINDVPLA GDRFVVFGDE
490 500 510 520 530 540
KQARRIGEAR HEASVIQQRQ ESKNVSLDNL FEQMKQGEMK DLNVIIKGDV QGSVEALAAS
550 560 570 580 590 600
LMKIDVEGVN VRIIHTAVGA INESDVTLAN ASNGIIIGFN VRPDAGAKRA AEAENVDMRL
610 620 630 640 650 660
HRVIYNVIEE IESAMKGLLD PEFEEQVIGQ AEVRQTFKVS KVGTIAGSYV TEGKITRNAG
670 680 690 700 710
VRVIRDGIVL FEGELDTLKR FKDDAKEVAQ GYECGITIEK YNDLKEGDII EAFEMVEIQR