Q5HKH9

PR
Gene name
pflB (SERP2366)
Protein name
Formate acetyltransferase
Names
Pyruvate formate-lyase
Species
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
KEGG Pathway
ser:SERP2366
EC number
2.3.1.54: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

583-666 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5HKH9

Entry ID Method Resolution Chain Position Source
AF-Q5HKH9-F1 Predicted AlphaFoldDB

No variants for Q5HKH9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5HKH9

No associated diseases with Q5HKH9

3 regional properties for Q5HKH9

Type Name Position InterPro Accession
domain Glycine radical domain 623 - 748 IPR001150
domain Pyruvate formate lyase domain 5 - 618 IPR004184
conserved_site Formate C-acetyltransferase glycine radical, conserved site 718 - 726 IPR019777

Functions

Description
EC Number 2.3.1.54 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
formate C-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate.

1 GO annotations of biological process

Name Definition
glucose metabolic process The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLETNNHTNA WQGFKTGRWN KNIDVREFIQ LNYSLYEGDD EFLEGPTKAT ETLWDQVMQL
70 80 90 100 110 120
SKEERERGGM WDMDTKVAST ITSHDAGYLD KDLEKVVGVQ TEKPFKRSMQ PFGGIRMAKA
130 140 150 160 170 180
ACEAYGYELD PETEKIFTEY RKTHNQGVFD AYSREMLNCR KAGIITGLPD AYGRGRIIGD
190 200 210 220 230 240
YRRVALYGVD FLMEQKLKDF NTMSTEMSED VIRLREELSE QYRSLQDLKE LGQKYGFDIS
250 260 270 280 290 300
RPATNFKEAV QWLYLAYLAA IKEQNGAAMS LGRTSTFLDI YAERDLQNGD ITEQEVQEII
310 320 330 340 350 360
DHFIMKLRIV KFARTPEYNE LFSGDPTWVT ESIGGVGIDG RPMVTKNSFR FLHSLDNLGP
370 380 390 400 410 420
APEPNLTVLW STRLPENFKI YCAKMSIKTS SIQYENDDLM RESYGDDYGI ACCVSAMKIG
430 440 450 460 470 480
KQMQFFGARA NLAKALLYAI NGGKDEKSGK QVGPSYEGIK SDVLDYDEVF ERYEKMMDWL
490 500 510 520 530 540
AGVYINSLNI IHYMHDKYSY ERLEMALHDT EIIRTMATGI AGLSVAADSL SAIKYAQVKP
550 560 570 580 590 600
IRNEEGLVTD FEIEGDFPKY GNNDSRVDEI AVDLVERFMT KLRSHKTYRN SEHTMSVLTI
610 620 630 640 650 660
TSNVVYGKKT GNTPDGRKAG EPFAPGANPM HGRDQKGALS SLSSVAKIPY DCCKDGISNT
670 680 690 700 710 720
FSIVPKSLGK EEVDQNKNLT SMLDGYAMQH GHHLNINVFN RETLIDAMEH PEEYPQLTIR
730 740
VSGYAVNFIK LTREQQLDVI SRTFHESM