Q5HKB0

PR
Gene name
copB (SERP2438)
Protein name
Probable copper-transporting P-type ATPase B
Names
Species
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
KEGG Pathway
ser:SERP2438
EC number
7.2.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-55 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5HKB0

Entry ID Method Resolution Chain Position Source
AF-Q5HKB0-F1 Predicted AlphaFoldDB

No variants for Q5HKB0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5HKB0

No associated diseases with Q5HKB0

2 regional properties for Q5HKB0

Type Name Position InterPro Accession
ptm P-type ATPase, phosphorylation site 367 - 373 IPR018303
domain P-type ATPase, haloacid dehalogenase domain 347 - 614 IPR044492

Functions

Description
EC Number 7.2.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
metal ion binding Binding to a metal ion.
P-type monovalent copper transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu+(in) -> ADP + phosphate + Cu+(out).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNHSNQMHHD NHESHNHHSG HAHHHGNFKV KFFVSLIFAI PIILLSPLMG VNLPFQFTFP
70 80 90 100 110 120
GSEWVVLILS TILFFYGGKP FLSGGKDEIA TKKPGMMTLV ALGISVAYIY SLYAFYMNNF
130 140 150 160 170 180
SSATGHTMDF FWELATLILI MLLGHWIEMN AVGNAGDALK KMAELLPNSA IKVMDNGQRE
190 200 210 220 230 240
EVKISDIMTD DIVEVKAGES IPTDGIIVQG QTSIDESLVT GESKKVQKNQ NDNVIGGSIN
250 260 270 280 290 300
GSGTIQVKVT AVGEDGYLSQ VMGLVNQAQN DKSSAELLSD KVAGYLFYFA VSVGVISFIV
310 320 330 340 350 360
WMLIQNDVDF ALERLVTVLV IACPHALGLA IPLVTARSTS IGAHNGLIIK NRESVEIAQH
370 380 390 400 410 420
IDYVMMDKTG TLTEGNFSVN HYESFKNDLS NDTILSLFAS LESQSNHPLA ISIVDFAKSK
430 440 450 460 470 480
NVSFTNPQDV NNIPGVGLEG LIHNKTYKIT NVSYLDQHGF EYDNDLFIKL AQQGNSISYL
490 500 510 520 530 540
IEDQQVIGMI AQGDQIKESS KQMVADLLSR NITPVMLTGD NNEVAHAVAK ELGISDVHAQ
550 560 570 580 590 600
LMPEDKESII KDYQSNGNKV MMVGDGINDA PSLIRADIGI AIGAGTDVAV DSGDIILVKS
610 620 630 640 650 660
NPSDIIHFLT LSNNTMRKMV QNLWWGAGYN IVAVPLAAGI LAFIGLILSP AIGAILMSLS
670
TVIVAINAFT LKLK