Q5HEL7
Gene name |
pcrA (SACOL1966) |
Protein name |
ATP-dependent DNA helicase PcrA |
Names |
|
Species |
Staphylococcus aureus (strain COL) |
KEGG Pathway |
sac:SACOL1966 |
EC number |
5.6.2.4: Enzymes altering nucleic acid conformation |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5HEL7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5HEL7-F1 | Predicted | AlphaFoldDB |
No variants for Q5HEL7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5HEL7 | |||||
No associated diseases with Q5HEL7
Functions
| Description | ||
|---|---|---|
| EC Number | 5.6.2.4 | Enzymes altering nucleic acid conformation |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA helicase activity | Unwinding of a DNA helix, driven by ATP hydrolysis. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA unwinding involved in DNA replication | The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNALLNHMNT | EQSEAVKTTE | GPLLIMAGAG | SGKTRVLTHR | IAYLLDEKDV | SPYNVLAITF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TNKAAREMKE | RVQKLVGDQA | EVIWMSTFHS | MCVRILRRDA | DRIGIERNFT | IIDPTDQKSV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IKDVLKNENI | DSKKFEPRMF | IGAISNLKNE | LKTPADAQKE | ATDYHSQMVA | TVYSGYQRQL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SRNEALDFDD | LIMTTINLFE | RVPEVLEYYQ | NKFQYIHVDE | YQDTNKAQYT | LVKLLASKFK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NLCVVGDSDQ | SIYGWRGADI | QNILSFEKDY | PEANTIFLEQ | NYRSTKTILN | AANEVIKNNS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ERKPKGLWTA | NTNGEKIHYY | EAMTERDEAE | FVIREIMKHQ | RNGKKYQDMA | ILYRTNAQSR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VLEETFMKSN | MPYTMVGGQK | FYDRKEIKDL | LSYLRIIANS | NDDISLQRII | NVPKRGVGPS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SVEKVQNYAL | QNNISMFDAL | GEADFIGLSK | KVTQECLNFY | ELIQSLIKEQ | EFLEIHEIVD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EVLQKSGYRE | MLERENTLES | RSRLENIDEF | MSVPKDYEEN | TPLEEQSLIN | FLTDLSLVAD |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IDEADTENGV | TLMTMHSAKG | LEFPIVFIMG | MEESLFPHIR | AIKSEDDHEM | QEERRICYVA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| ITRAEEVLYI | THATSRMLFG | RPQSNMPSRF | LKEIPESLLE | NHSSGKRQTI | QPKAKPFAKR |
| 670 | 680 | 690 | 700 | 710 | 720 |
| GFSQRTTSTK | KQVLSSDWNV | GDKVMHKAWG | EGMVSNVNEK | NGSIELDIIF | KSQGPKRLLA |
| QFAPIEKKED |