Q5H873
Gene name |
HMT/HLT |
Protein name |
13-hydroxylupanine O-tigloyltransferase |
Names |
(-)-13alpha-hydroxymultiflorine/(+)-13alpha-hydroxylupanine O-tigloyltransferase, HMT/HLTase, Quinolizidine alkaloid O-tigloyltransferase |
Species |
Lupinus albus (White lupine) (Lupinus termis) |
KEGG Pathway |
ag:BAD89275 |
EC number |
2.3.1.93: Transferring groups other than amino-acyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5H873
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5H873-F1 | Predicted | AlphaFoldDB |
No variants for Q5H873
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5H873 | |||||
No associated diseases with Q5H873
No regional properties for Q5H873
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5H873 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.1.93 | Transferring groups other than amino-acyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| 13-hydroxylupinine O-tigloyltransferase activity | Catalysis of the reaction: 13-hydroxylupanine + 2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyloxy)lupanine + CoA. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| alkaloid biosynthetic process | The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases). |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAPQTQSLVF | KVRRNPQELV | TPAKPTPKEF | KLLSDIDDQT | SLRSLTPLVT | IYRNNPSMEG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KDPVEIIREA | LSKTLVFYYP | FAGRLRNGPN | GKLMVDCTGE | GVIFIEADAD | VTLDQFGIDL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HPPFPCFDQL | LYDVPGSDGI | LDSPLLLIQV | TRLKCGGFIF | AVRLNHAMCD | AIGMSQFMKG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LAEIARGEPK | PFILPVWHRE | LLCARNPPKV | TFIHNEYQKP | PHDNNNNNFI | LQHSSFFFGP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NELDAIRRLL | PYHHSKSTTS | DILTAFLWRC | RTLALQPENP | NHEFRLLYIL | NARYGRCSFN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PPLPEGFYGN | AFVSPAAIST | GEKLCNNPLE | YALELMKEAK | SKGTEEYVHS | VADLMVIKGR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PSYFYNDVGY | LEVSDLTKAR | FRDVDFGWGK | AVYGGATQGY | FSSILYVSYT | NSKGVEGIMA |
| 430 | 440 | 450 | |||
| LTSLPTKAME | RFEKELDDLF | KTKDKSQILR | SHI |