Q5GT19

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Wolbachia sp subsp Brugia malayi (strain TRS)
KEGG Pathway
wbm:Wbm0266
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

5-80 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5GT19

Entry ID Method Resolution Chain Position Source
AF-Q5GT19-F1 Predicted AlphaFoldDB

No variants for Q5GT19

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5GT19

No associated diseases with Q5GT19

8 regional properties for Q5GT19

Type Name Position InterPro Accession
conserved_site SEC-C motif 844 - 861 IPR004027
domain SecA DEAD-like, N-terminal 5 - 389 IPR011115
domain SecA Wing/Scaffold 610 - 818 IPR011116
domain SecA, preprotein cross-linking domain 227 - 345 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 88 - 246 IPR014001
domain SecA motor DEAD 2 - 612 IPR014018
conserved_site SecA conserved site 487 - 502 IPR020937
domain SecA, C-terminal helicase domain 407 - 582 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSFFFKRTFG SINKKIIKSF RKIVEQINAL ETKMQSLSDE ELADKTEEFK RELKNGKTLN
70 80 90 100 110 120
DLLVPAFAVV REASRRFLNM RHFDVQLIGG MVLHNGMVSE MKTGEGKTLV ATLAAYLNSL
130 140 150 160 170 180
EGKGVHVVTV NDYLAKRDTE WMSKLYNSLG VSVAFITNDL TDEERKEAYS ADIVYSTNNE
190 200 210 220 230 240
LAFDYLRDNM KFSREDMVQR GFNYAIVDEV DSILIDEART PLIISGPVEE NNQIYKHIDK
250 260 270 280 290 300
IVTKLVDSDY EVDEKGRAVF LTEDGISQVE ELLRSYNLIS EKSSLYDAGN MIMTHYIDQA
310 320 330 340 350 360
LRAHKLFTAD KDYIVKDGKV VIIDEFTGRM MEGRRYSDGL HQALEAKENL EIQYENQTLA
370 380 390 400 410 420
SVTFQNYFRM YNKLSGMTGT AATEAEELRD IYRLNVVKIP TNVTVKRIDV DDEIYGTEKE
430 440 450 460 470 480
KFNAVLKFIK ECHKRLQPVL VGTVSIENSE KLSALLRNHF LRHSVLNARY HEQEAYIIAQ
490 500 510 520 530 540
AGVPGNITIA TNMAGRGTDI QLGGNAEMIA KVELKKIKNA DEREKKYQEI IERVKRDKEI
550 560 570 580 590 600
AMKAGGLCVI GTERHESRRI DDQLRGRSGR QGDPGLSKFF LSLEDDLMRI FGSDRMRSFL
610 620 630 640 650 660
KRVGLKNNEA IHHPWINKAL EKAQKKVEAR NYDVRKSLLK FDDVINNQRK VIFEQRNHIL
670 680 690 700 710 720
GNEINDLFEV YSEVNKSVME SIVQGGYYED YVEDIAKEFH IRYGITLDKK DLAKFLNKQE
730 740 750 760 770 780
ALDYINGKVK EFFTEKEKYF NGQQTTDLWN TIVKQVMIMT LDHLWREHLS ILESLRQSIG
790 800 810 820 830 840
LRAMGQKDPL NEFKREAFLI FECMLERGKE LTIHRLAHFK LVDNQEVGGR LHPTRKDNLP
850 860
KVSRNDKCPC NSGKKYKHCH GAVTVMN