Q5GH59
Gene name |
Xkr4 |
Protein name |
XK-related protein 4 |
Names |
|
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:297801 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5GH59
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5GH59-F1 | Predicted | AlphaFoldDB |
No variants for Q5GH59
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5GH59 | |||||
No associated diseases with Q5GH59
No regional properties for Q5GH59
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5GH59 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| phospholipid scramblase activity | Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism. |
| protein homodimerization activity | Binding to an identical protein to form a homodimer. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| apoptotic process involved in development | Any apoptotic process that is involved in anatomical structure development. |
| engulfment of apoptotic cell | The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte. |
| phosphatidylserine exposure on apoptotic cell surface | A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q5GH67 | Xkr4 | XK-related protein 4 | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARPPPLLVQ | KPSFLVEACC | SPSPATHLAP | YHTQPGARTP | STIQRDLLFP | IPRRCHARSS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PRPPALGGGP | TQRLQHAARS | AHPIPPSVKE | IHPTFSEIPR | ARASDCCAAA | LGVQHWPARH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PHPPLPSISL | AVDYYLLGQR | WWFGLTLFFV | VLGSLSVQVF | SFRWFVHDFS | TEDSATTTAS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TCQQPGADCK | TVVSSGSAAG | EGEARPSTPQ | RQASNASKSN | IAATNSGSNS | NGATRTSGKH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RSASCSFCIW | LLQSLIHILQ | LGQVWRYLHT | IYLGIRSRQS | GESSRWRFYW | KMVYEYADVS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| MLHLLATFLE | SAPQLVLQLC | IIVQTHSLQA | LQGFTAAASL | VSLAWALASY | QKALRDSRDD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KKPISYMAVI | IQFCWHFFTI | AARVITFALF | ASVFQLYFGI | FIVLHWCIMT | FWIVHCETEF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| CITKWEEIVF | DMVVGIIYIF | SWFNVKEGRT | RCRLFIYYFV | ILLENTALSA | LWYLYKAPQI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ADAFAIPALC | VVFSSFLTGV | VFMLMYYAFF | HPNGPRFGQS | PSCACDDPAT | AFSMPPEVAT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| STLRSISNNR | SVASDRDQKF | AERDGCVPVF | QVRPTAPPTP | SSRPPRIEES | VIKIDLFRNR |
| 610 | 620 | 630 | 640 | ||
| YPAWERHVLD | RSLRKAILAF | ECSPSPPRLQ | YKDDALIQER | LEYETTL |