Q5EAJ7

PR
Gene name
MVP
Protein name
Major vault protein
Names
MVP
Species
Strongylocentrotus purpuratus (Purple sea urchin)
KEGG Pathway
spu:575735
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

401-480 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5EAJ7

Entry ID Method Resolution Chain Position Source
AF-Q5EAJ7-F1 Predicted AlphaFoldDB

No variants for Q5EAJ7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5EAJ7

No associated diseases with Q5EAJ7

16 regional properties for Q5EAJ7

Type Name Position InterPro Accession
binding_site IQ motif, EF-hand binding site 665 - 694 IPR000048
repeat Major vault protein, N-terminal 62 - 122 IPR002499-1
repeat Major vault protein, N-terminal 123 - 174 IPR002499-2
repeat Major vault protein, N-terminal 175 - 227 IPR002499-3
repeat Major vault protein, N-terminal 228 - 282 IPR002499-4
repeat Major vault protein, N-terminal 284 - 332 IPR002499-5
repeat Major vault protein, N-terminal 333 - 387 IPR002499-6
domain Major vault protein, shoulder domain 511 - 662 IPR021870
domain Major vault protein repeat domain 3 459 - 520 IPR040989
domain Major vault protein repeat domain 2 56 - 114 IPR041134-1
domain Major vault protein repeat domain 2 279 - 325 IPR041134-2
domain Major vault protein repeat domain 4 383 - 442 IPR041136
domain Major vault protein repeat domain 119 - 159 IPR041139-1
domain Major vault protein repeat domain 172 - 211 IPR041139-2
domain Major vault protein repeat domain 224 - 267 IPR041139-3
domain Major vault protein repeat domain 330 - 371 IPR041139-4

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASKRGSNQD ESIFRIPPYY YIHVLDHNDN VTKVVVGPKT YIRQDHERVI FGPEKMITIP
70 80 90 100 110 120
PRHYCIIENP VVRNDTDQVV YDNLGQVKLF HADQEIRLAR EPFPLYPGEV LKQAVTALKV
130 140 150 160 170 180
VQANAALRLR AILDFEDGTQ KRVAGDEWLF EGPGTYIPRK EVVVDETIRA TIIRPNQAIK
190 200 210 220 230 240
LRARKETNDR EGTARVTGEE WQVKKVGAYL PGAYEEVVDT VNAYVLTEKN ALHLRATRTF
250 260 270 280 290 300
VDMKGKTRKN GEEWLINMAD TDAHIPDVYE EVVGVVDINT LTNRQYCVIV DPVGPDGKPQ
310 320 330 340 350 360
LGQKKLVKGE VSFFLQPGET LEQGIQSVFI LGEDEGLILR AQESFKDANA AGAVRQPGDR
370 380 390 400 410 420
WMIRGPCEYV PTVELEVVTR RKAIPLDENE GVYIRDTKTG KVRAVTGETY MLSQDEELWA
430 440 450 460 470 480
KELSPAVEEL LQSAKDPVAE RSDRRGDRAA PRAREKTRVI SFRVPHNAAV QIYDYKEKKA
490 500 510 520 530 540
RVVFGPELVM LGPDEQFTQL SLSGGKPKRP NVIKALCLLL GPDFCTDIIT IETADHARLQ
550 560 570 580 590 600
LQLSYNWHFD VPDKTDVAAS AKLFSVPDFI GDACKAIASR IRGAVAGVQF DDFHKNSAKI
610 620 630 640 650 660
IRASVFGFDE KNKVRERFLF PQNSLVITSI DIQSVEPVDQ RTRDALQKSV QLAIEITTNS
670 680 690 700 710 720
QEATARHEAE RLEQEARGRL ERQKIMDEAE AEKSRKELLE LQANSAAVES TGQAKAEAQS
730 740 750 760 770 780
RAEAARIEGE AAVDQARLKA EAAKIESESE LQRLTNAREA ETKYVREQNA LEVNKTKQMS
790 800 810 820 830 840
DIETERFRNM VQSIGADTIK AMAMAGPEMQ VKLLSSLGLK STLITDGSTP INLFNTAQGL
850
LGGFSAKRGI EHVEEED