Q5E863

PR
Gene name
surA
Protein name
Chaperone SurA
Names
Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA
Species
Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri)
KEGG Pathway
vfi:VF_0288
EC number
5.2.1.8: Cis-trans isomerases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

22-154 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5E863

Entry ID Method Resolution Chain Position Source
AF-Q5E863-F1 Predicted AlphaFoldDB

No variants for Q5E863

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5E863

No associated diseases with Q5E863

2 regional properties for Q5E863

Type Name Position InterPro Accession
domain SpoVT-AbrB domain 29 - 74 IPR007159
domain Toxin SymE-like 20 - 71 IPR014944

Functions

Description
EC Number 5.2.1.8 Cis-trans isomerases
Subcellular Localization
  • Periplasm
  • Is capable of associating with the outer membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
outer membrane-bounded periplasmic space The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.

3 GO annotations of molecular function

Name Definition
peptide binding Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds.
peptidyl-prolyl cis-trans isomerase activity Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
unfolded protein binding Binding to an unfolded protein.

3 GO annotations of biological process

Name Definition
Gram-negative-bacterium-type cell outer membrane assembly The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures.
protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
protein stabilization Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKNWKFPLIS TLLLLLTINV HAAPVELDRV VAIVDEGVVL QSDIDTSLKT VKINAQEKGQ
70 80 90 100 110 120
PLPDEAVLRE QVLEKLIVDT IQSQQAEKMG IRIDDTRLEA ALNDIAKENN MTLAQLQQKT
130 140 150 160 170 180
AAQGLPYANF REQIRKEIAA SEARNAQVRR RINILPQEVE SLAQLLAEET QATVQYKISH
190 200 210 220 230 240
IQLRVEDGAT QADKEALEKQ AEDLTERLKQ GADFATMAYT YSKGPKALQG GDWGWMRKEE
250 260 270 280 290 300
MPTIFADQIT GQGKNSIIGP FRSGVGFHIL KIDDVKGLET VAVTEVNARH ILIKTSVIMS
310 320 330 340 350 360
DEGAQRLLNT IIDDIKSGKE TFADMAQRYS QDPGSAANDG ELGFQTPDLY VPEFKHQVET
370 380 390 400 410 420
LPVGQISAPF KTVHGWHIAE VLERRQVDRT DAAMKNKAYR ILLNRKFNEE AGAWLQEIRA
430
SAYVEILQDD DGEDDNE