Q5E763

PR
Gene name
guaA
Protein name
GMP synthase [glutamine-hydrolyzing]
Names
GMP synthetase, Glutamine amidotransferase
Species
Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri)
KEGG Pathway
vfi:VF_0638
EC number
6.3.5.2: Carbon--nitrogen ligases with glutamine as amido-N-donor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

311-388 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5E763

Entry ID Method Resolution Chain Position Source
AF-Q5E763-F1 Predicted AlphaFoldDB

No variants for Q5E763

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5E763

No associated diseases with Q5E763

2 regional properties for Q5E763

Type Name Position InterPro Accession
domain Septum formation inhibitor MinC, C-terminal 131 - 231 IPR005526
domain Septum formation inhibitor MinC, N-terminal 9 - 79 IPR007874

Functions

Description
EC Number 6.3.5.2 Carbon--nitrogen ligases with glutamine as amido-N-donor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GMP synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+).
pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups.

1 GO annotations of biological process

Name Definition
glutamine metabolic process The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTTNIHDQRI LILDFGSQYT QLVARRIREI GVYCELWSWD VEESDIRDFN PDGIILSGGP
70 80 90 100 110 120
ESVTEENSPR APQYVFDSGV PVFGVCYGMQ TMAEQLGGKV ATSTEREFGY AAVQVTGESA
130 140 150 160 170 180
LFKDLEATQD VWMSHGDKVV EIPSDFVKIA ETETCPYAAM ANEEKKYYGV QFHPEVTHTK
190 200 210 220 230 240
NGMKMLENFV LNVCGCEGLW TSASIIEDAV ARIKEQVGDD EVILGLSGGV DSSVVAMLAH
250 260 270 280 290 300
RAIGDKLTCV FVDNGLLRLN EADQVMEMFG NKFGLNIVHV NAEQRFLDAL EGESDPETKR
310 320 330 340 350 360
KIIGHVFVDI FDEESKKLKN AKWLAQGTIY PDVIESAASK TGKAHVIKSH HNVGGLPDDM
370 380 390 400 410 420
EMGLVEPLRE LFKDEVRKIG LELGLPYNML YRHPFPGPGL GVRVLGEIKK EYCDLLRRAD
430 440 450 460 470 480
AIFIEELHNA DLYNKVSQAF TVFLPVRSVG VMGDGRKYDW VVSLRAVETI DFMTAHWAHL
490 500 510
PYDFLGKVSN RIINEVNGIS RVVYDISGKP PATIEWE