Q5DRE3
Gene name |
PCDHA9 |
Protein name |
Protocadherin alpha-9 |
Names |
PCDH-alpha-9 |
Species |
Pan troglodytes (Chimpanzee) |
KEGG Pathway |
ptr:100034716 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5DRE3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5DRE3-F1 | Predicted | AlphaFoldDB |
1 variants for Q5DRE3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs25144365 | 505 | W>S | No | Ensembl |
No associated diseases with Q5DRE3
11 regional properties for Q5DRE3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Cadherin-like | 8 - 133 | IPR002126-1 |
| domain | Cadherin-like | 134 - 242 | IPR002126-2 |
| domain | Cadherin-like | 242 - 350 | IPR002126-3 |
| domain | Cadherin-like | 351 - 565 | IPR002126-4 |
| domain | Cadherin-like | 588 - 678 | IPR002126-5 |
| domain | Cadherin, N-terminal | 30 - 111 | IPR013164 |
| conserved_site | Cadherin conserved site | 230 - 240 | IPR020894-1 |
| conserved_site | Cadherin conserved site | 338 - 348 | IPR020894-2 |
| conserved_site | Cadherin conserved site | 443 - 453 | IPR020894-3 |
| conserved_site | Cadherin conserved site | 553 - 563 | IPR020894-4 |
| domain | Cadherin, C-terminal catenin-binding domain | 800 - 933 | IPR031904 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium ion binding | Binding to a calcium ion (Ca2+). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| homophilic cell adhesion via plasma membrane adhesion molecules | The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell. |
| nervous system development | The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLYSSRGDPE | GQPLLLSLLI | LAMWVVGSGQ | LHYSVPEEAK | HGTFVGRIAQ | DLGLELAELV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PRLFQLDSKG | RGDLLEVNLQ | NGILFVNSRI | DREELCGRSA | ECSIHLEVIV | DRPLQVFHVD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VEVKDINDNP | PVFPATQKNL | FIAESRPLDS | RFPLEGASDA | DIGENALLTY | RLSPNEYFFL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DVPTSNQQVK | PLGLVLRKLL | DREETPELHL | LLTATDGGKP | ELTGTVQLLI | TVLDNNDNAP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VFDRTLYTVK | LPENVSIGTL | VIHPNASDLD | EGLNGDIIYS | FSSDVSPDIK | SKFHMDPLSG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AITVIGHMDF | EESRAHKIPV | EAVDKGFPPL | AGHCTVLVEV | VDVNDNAPQL | TIKTLSVPVK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EDAQLGTVIA | LISVTDLDAD | ANGQVTCSLT | PHVPFKLVST | YKNYYSLVLD | RALDRESVSA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| YELVVTARDG | GSPSLWATAR | VSVEVADVND | NAPAFAQPEY | TVFVKENNPP | GCHIFTVSAR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DADAQENALV | SYSLVERRLG | ERSLWSYVSV | HAESGKVYAL | QPLDHEELEL | LQFQVSARDA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| GVPPLGSNVT | LQVFVLDEND | NAPALLTPRM | RGTDGAVSEM | VLRSVGAGVV | VGKVLAVDAD |
| 610 | 620 | 630 | 640 | 650 | 660 |
| SGYNAWLSYE | LQPETASASI | PFRVGLYTGE | ISTTRALDET | DAPRQRLLVL | VKDHGEPALT |
| 670 | 680 | 690 | 700 | 710 | 720 |
| ATATVLVSLV | ESGQAPKSSS | RASVGATGPE | VTLVDVNVYL | IIAICAVSSL | LVLTLLLYTV |
| 730 | 740 | 750 | 760 | 770 | 780 |
| LRCSAMPTEG | ECAPGKPTLV | CSSAVGSWSY | SQQRRQRVCS | GEGPQKTDLM | AFSPGLSPCA |
| 790 | 800 | 810 | 820 | 830 | 840 |
| GSTERTGEPS | ASSDSSGKPR | QPNPDWRYSA | SLRAGMHSSV | HLEEAGILRA | GPGGPDQQWP |
| 850 | 860 | 870 | 880 | 890 | 900 |
| TVSSATPEPE | AGEVSPPVGA | GVNSNSWTFK | YGPGNPKQSG | PGELPDKFII | PGSPAIISIR |
| 910 | 920 | 930 | 940 | ||
| QEPANSQIDK | SDFITFGKKE | ETKKKKKKKK | GNKTQEKKEK | GNSTTDNSDQ |