Q5BFU1

PR
Gene name
dbp4 (AN0589)
Protein name
ATP-dependent RNA helicase dbp4
Names
Species
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
KEGG Pathway
ani:AN0589.2
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

469-567 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5BFU1

Entry ID Method Resolution Chain Position Source
AF-Q5BFU1-F1 Predicted AlphaFoldDB

No variants for Q5BFU1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5BFU1

No associated diseases with Q5BFU1

6 regional properties for Q5BFU1

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 199 - 207 IPR000629
domain Helicase, C-terminal 279 - 438 IPR001650
domain DEAD/DEAH box helicase domain 72 - 241 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 67 - 270 IPR014001
domain RNA helicase, DEAD-box type, Q motif 48 - 76 IPR014014
domain Domain of unknown function DUF4217 429 - 492 IPR025313

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
small-subunit processome A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.

6 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
box C/D RNA binding Binding to a box C/D small nucleolar RNA.
identical protein binding Binding to an identical protein or proteins.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.
U3 snoRNA binding Binding to a U3 small nucleolar RNA.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAPSNGHRNG KHAKSSNKSG NLKRKRVQED LSSLIKRVED LDLKAKYESF SDLPISEPTL
70 80 90 100 110 120
SGLTSSHFKT LTDIQSRAIS HALKGRDVLG AAKTGSGKTL AFLVPILENL YRKQWSDHDG
130 140 150 160 170 180
LGALIISPTR ELAIQIFEVL RKIGRYHTFS AGLVIGGKSL KEEQERLGRM NILVCTPGRM
190 200 210 220 230 240
LQHLDQTAFF ETYNLQMLVL DEADRIMDMG FQKTVDAIIG HLPPERQTLL FSATQTKKVS
250 260 270 280 290 300
DLARLSLQDP EYVAVHEAAS SATPSKLQQH YVVTPLPQKL DTLWSFIRSN LKSKTIVFMS
310 320 330 340 350 360
SGKQVRFVYE SFRHMQPGIP LLHLHGRQKQ GGRLDITTRF SQAQHAVLFS TDVAARGLDF
370 380 390 400 410 420
PAVDWVIQLD CPEDADTYIH RVGRTARYER DGRAVLFLDP SEEKGMLRRL EQKRVTVERI
430 440 450 460 470 480
NVRANKQQSI KNQLQNMCFK DPELKYLGQK AFISYVKSVY IQKDKETFNL KELKLDDFAA
490 500 510 520 530 540
SLGLPGAPRI KFIKGDDTKE RKNASRATAY LTSGDEESDE EGGKKKQPKE KEVRTKYDRM
550 560 570 580 590 600
FERRNQDVLA EHYSKLINDD GTIADSKNTE EADEDEDFLS VKRRFDAGDD ALHAEDSSAS
610 620 630 640 650 660
DSDASDSEAE DHTEKKDPKV VKISDKDTLV IDSKRREKLL KSKKKLLKFK GKGTKLVYDD
670 680 690 700 710 720
EGNAHELYEM EDEEAFKARG DAKEQQARFL AEEAARTQRA DMEDKEIAKQ KRREKKEKRK
730 740 750 760 770 780
ARERELLAEE EREERVAQLV PFDEDEDMGD AGGYSQSSDG EEEAPRPSKR AKVEEPKAVP
790 800 810
WYKKEAGKKN DAGEKQIQTL EDLESLATGL LG