Q5BCI0

PR
Gene name
mak5 (AN1750)
Protein name
ATP-dependent RNA helicase mak5
Names
Species
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
KEGG Pathway
ani:AN1750.2
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-56 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5BCI0

Entry ID Method Resolution Chain Position Source
AF-Q5BCI0-F1 Predicted AlphaFoldDB

No variants for Q5BCI0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5BCI0

No associated diseases with Q5BCI0

5 regional properties for Q5BCI0

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 348 - 356 IPR000629
domain Helicase, C-terminal 460 - 626 IPR001650
domain DEAD/DEAH box helicase domain 208 - 411 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 203 - 438 IPR014001
domain RNA helicase, DEAD-box type, Q motif 184 - 212 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGQKRQRDQK GPTLHVRKRK RTGKPTNVAE RESKPEVVVG VDDLNWKEVA LPDRLDNFEG
70 80 90 100 110 120
FFGLEEIEGV DIVRPQGNGQ LRFKSAPGKP GKSILKKPTP KSEETEFDDE WNGFSDEDLE
130 140 150 160 170 180
KKEGASTVNE VAKAADVNGK KGKDAKNKKD IKAKEPKKKL KEQKEKDGAQ AKDRSITSGL
190 200 210 220 230 240
SFAALEDEAD DDGADISAWE PLGLSPETLT SLSKLKFSTP TSVQKSCIPP ILDGHDVIGK
250 260 270 280 290 300
ASTGSGKTLA FGLPILEHYL ERERRKTIDS EEEKEKIPIA LILSPTRELA HQLQKHIYGL
310 320 330 340 350 360
ISNAPGVNAR TALLTGGLSV QKQQRLLETA DIVIGTPGRV WEVLRTGQGL IRRMQGIKFL
370 380 390 400 410 420
VIDEADRLLS EGHFKEVEDI LSSLDRVEDG GPPDEEDDSS EENVVPGVER QTLVFSATFH
430 440 450 460 470 480
RDLQQKLAGK GKWTGGDIMN KKESMEYLLQ KLNFREEKPK FIDVNPVSQM AEGLKEGIVE
490 500 510 520 530 540
CPAMEKDLYL YTLLLYHPKH RTLVFTNSIS AVRRITQLLQ TLQLPALALH SSMAQKARLR
550 560 570 580 590 600
SVERFSSSTA NPGTILVATD VAARGLDIKG IDFVIHYHAP RTADTYVHRS GRTARAGASG
610 620 630 640 650 660
KSVIICSPEE MVGVVRLAAK VHANMANGKK LPLESLELDR RIVSRVRQRV VLAARITDSN
670 680 690 700 710 720
IAKEKITTED NWLRNAAEDL GVEYDSDEFD QAKGWGRGRG RGRQERDRQV GSTSKAELAG
730 740 750 760
LRAELKELLS QRVNLGVSER YLTSGRVDIE ALLREEGNNS FLGQVDPLGF