Q5B6U6

PR
Gene name
atg9 (AN3734)
Protein name
Autophagy-related protein 9
Names
Species
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
KEGG Pathway
ani:AN3734.2
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-190 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5B6U6

Entry ID Method Resolution Chain Position Source
AF-Q5B6U6-F1 Predicted AlphaFoldDB

No variants for Q5B6U6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5B6U6

No associated diseases with Q5B6U6

4 regional properties for Q5B6U6

Type Name Position InterPro Accession
domain ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain 213 - 436 IPR000194
domain ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain 6 - 68 IPR004100
active_site ATPase, alpha/beta subunit, nucleotide-binding domain, active site 427 - 436 IPR020003
domain ATPsynthase alpha/beta subunit, N-terminal extension 84 - 204 IPR031686

Functions

Description
EC Number
Subcellular Localization
  • Preautophagosomal structure membrane ; Multi-pass membrane protein
  • Cytoplasmic vesicle membrane ; Multi-pass membrane protein
  • Golgi apparatus membrane ; Multi-pass membrane protein
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

7 GO annotations of cellular component

Name Definition
autophagosome A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.
cytoplasmic vesicle membrane The lipid bilayer surrounding a cytoplasmic vesicle.
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
phagophore assembly site Punctate structures proximal to the endoplasmic reticulum which are the sites where the Atg machinery assembles upon autophagy induction.
phagophore assembly site membrane A cellular membrane associated with the phagophore assembly site.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

4 GO annotations of biological process

Name Definition
autophagy of mitochondrion The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions.
late nucleophagy A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM.
lipid transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
protein localization to phagophore assembly site Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMASNVLSRL LPQTGQSVYE TIRQHDNDSD ASDVEERAGL VYDDDVNLGN RFSDRELEEA
70 80 90 100 110 120
MADATREGSS SPSDTFLTPQ IAQRGERSAS SGPRMRKPNN PRFMRSVTPR PEFVEDDLDD
130 140 150 160 170 180
DHDDDVPASL LMEGQHDDEY LRTRLPPPPS HHFSDPQPSR SARSPRREHI RTFAFVVGFT
190 200 210 220 230 240
TFLTNCIDYR LVRTSKSLDQ ILISKCTSRM SASSTFLLWL LCLFWIGKIF QLILDIRRLK
250 260 270 280 290 300
NMHDFYHYLL GVSDAEIQTI SWQEVVSRLM TLRDANPATA GAVSAFNRRL LGSQSKQRMD
310 320 330 340 350 360
AHDIANRLMR KENYLIALIN KDILDLTLPI PFLRNRQLFS RILEWNINLC IMDYVFNEQG
370 380 390 400 410 420
QLSSRQYTPL AEWKFREFNE LWHLFEKRIN LSYPYATRYV DQFPKDKTVQ VAGFVAFISG
430 440 450 460 470 480
ALASVLALAS ILDPELFLGF ELTHDRTTLF YLGVFGSVWA FARGMVPEET LVFDPEYALL
490 500 510 520 530 540
EVIQFTHYFP SHWKGKLHSD DVRREFAVLY QMKIIIFMEE ILSMIFTPFI LWFSLPKCSE
550 560 570 580 590 600
RVIDFFREFT VHVDGMGYLC SFAVFDFKKG TNVIPQGHIN QRDARQDPRV DYFSTKDGKM
610 620 630 640 650 660
LASYYGFLDN YGGNPRATNA NKRAFHPPPT FPSLGSPPFV GASNIGNRQD PIQARVNTAS
670 680 690 700 710 720
AALGQQSMLG ATRLGALGVG DTQSPAPSLL LDPQHQPSAS GFRATNHIAP HHRQRLGRPP
730 740 750 760 770 780
PAPVSESIID DNEPSIAAAR RPAPRRKSGQ LHTNSGSSEA LGAGDSNVED SWGMKSGGEV
790 800 810
NDEDAEENVD DVVGGAGVLG LIQQFQKVNK DNRPRAAVGL