Q5APM7

PR
Gene name
MSS116 (CAALFM_C108810CA, CaO19.12201, CaO19.4739)
Protein name
ATP-dependent RNA helicase MSS116, mitochondrial
Names
Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
KEGG Pathway
cal:CAALFM_C108810CA
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-102 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5APM7

Entry ID Method Resolution Chain Position Source
AF-Q5APM7-F1 Predicted AlphaFoldDB

No variants for Q5APM7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5APM7

No associated diseases with Q5APM7

3 regional properties for Q5APM7

Type Name Position InterPro Accession
domain Helicase, C-terminal 332 - 501 IPR001650
domain DEAD/DEAH box helicase domain 111 - 287 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 106 - 318 IPR014001

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Mitochondrion matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

4 GO annotations of biological process

Name Definition
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
regulation of translation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
RNA splicing The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLKQLSRSLG IRSSPIVANL IRSKQVCTRG FHISLVKQNT SSKVNEITDI TSDSLKVKED
70 80 90 100 110 120
AAGSDLPSTK TDKKSKSESF QPVKFEDFKG KGYIHDSIIN SLHKNDFKEL TPIQQKSLVP
130 140 150 160 170 180
IFNTEKGLVC RAKTGTGKTL AFAVPTLQYA YKNRGKGVST VVLVPTRDLA FQIEEEYRKL
190 200 210 220 230 240
ISHLKYNERP NLELIIGGQR TSFNPRRPAE IVIATPGRLE KELQTDRKLA KCFSNVTYRI
250 260 270 280 290 300
YDEADRLLDV GFESVLNEID GLLYKVRTTP KPIKSLLFSA TVDEAISEFS KKHIHPEYEF
310 320 330 340 350 360
LNTVTKDDLE IPENIHQQLI ECTDGIDKVN VSLSELHGIM KQHNDYKVIV FLPTKTAVDW
370 380 390 400 410 420
FYEYITNALD DELFELFSKP PRVFMLHGGR SVRQRSAALK GFKVAKKGIL ISTDVAARGI
430 440 450 460 470 480
DVKDVTNVMQ MFPSVEIADY IHKVGRTGRA GKKGKASLFA TPAELPYVSL LKRKRKVKFQ
490 500 510 520 530 540
EVIQSEKLNS SNIIDQIESP LDSTKEFLAT MVGYLQQLQS AHRLDYDSLV IENMELYRKL
550 560 570 580 590 600
VRDDKAMLES RILSRIGKGI SAHVKRRYFT RTRYQSHDDA EFDSYSDFSR SGMSQRPRSN
610 620 630 640 650 660
DRSSKMTFNG RGKYGNNRNN DWSYQNKNRY NNNNNRQTER SYDSDRKSHN DWKYEKKFEH
RRIRDHDE