Q5APG6
Gene name |
CEF1 (CAALFM_C109370WA, CaO19.12262, CaO19.4799) |
Protein name |
Pre-mRNA-splicing factor CEF1 |
Names |
|
Species |
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
KEGG Pathway |
cal:CAALFM_C109370WA |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5APG6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5APG6-F1 | Predicted | AlphaFoldDB |
No variants for Q5APG6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5APG6 | |||||
No associated diseases with Q5APG6
No regional properties for Q5APG6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5APG6 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleolar ring | Ring-like structures located at the nucleolar periphery where several nuclear factors are reversibly aggregated and sequestered during acute heat stress. |
| post-mRNA release spliceosomal complex | A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, including U5. |
| Prp19 complex | A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p. |
| spliceosomal complex | Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA cis splicing, via spliceosome | The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript. |
| mRNA splicing, via spliceosome | The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAPPLYVKGG | VWTNVEDEIL | KAAIQKYGIY | QWERISSLLP | KKSAKQVKAR | WVEYLSPLLN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KTDWTKEEDE | KLLNLHKIFP | NQWRSISNIL | NRTAVQCVER | YQKLIDEAAG | IKPGDDEENL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GLSGPGIETL | PAVGASSGLA | VGEMNLNPES | KPARPDDEDL | PDDEREMLAE | AKARLGNIQG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KKAKRKARER | MLEESKRIAL | LQKRRELKSA | GINVKLTTRN | KKKRKEFDYN | ADIPHEIIPQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AGPYDTAEEL | KQNDFEKQQF | GQQVSTKGIS | MKDIDDRIAK | EESRRKKEIE | KKKLERKREF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NAAASLISEH | EDSKRRKLNL | PEPGTHNFEK | TKSDVLTLTN | QANNKLSEKE | IARNQNKKRA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AVAQLIKATF | ERLPPPKHET | GEILPFVSTN | ILEFRNDVNA | NDISDIAGAK | LPDETATNVS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TLISRVVQRE | LPIPHPNNLR | DLSTVKFDTL | VDKLIAEECH | RLIRSDYKQY | HDTTINGVST |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DKYDRDLLEK | INQDIDKEFA | QMDVSTVHSF | EDYVLPKNFK | VAESIIENLH | TFHNENEKLT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| NKILESTNYE | DQRDQKLQQL | THLWRELSDV | NLSYSIEKKL | FELESSAIDK | ELLRLRSEID |
| KLNKKIETLR |