Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q5APB6

Entry ID Method Resolution Chain Position Source
AF-Q5APB6-F1 Predicted AlphaFoldDB

No variants for Q5APB6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5APB6

No associated diseases with Q5APB6

4 regional properties for Q5APB6

Type Name Position InterPro Accession
domain Protein kinase domain 30 - 281 IPR000719
domain SARAH domain 433 - 480 IPR011524
binding_site Protein kinase, ATP binding site 36 - 59 IPR017441
domain Mst1 SARAH domain 433 - 480 IPR024205

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
nuclear protein quality control by the ubiquitin-proteasome system The chemical reactions and pathways resulting in the breakdown of misfolded proteins via a mechanism in which the proteins are transported to the nucleus for ubiquitination, and then targeted to proteasomes for degradation.
proteasome localization Any process in which the proteasome is transported to, or maintained in, a specific location.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMSTNFQWPG TNKNDNTEVS VETPSSTDPH VPRYPFTAMS HATASTTMKK RKRDDFDGDK
70 80 90 100 110 120
STTITMNTTT TRKYIQSSLG SSKFKKAKTP KISGQPLPLP RLIESLDKSN LQKLVQDLIT
130 140 150 160 170 180
VHPELQSTLI KISPRPSIQD SIQLLQDKFD MIISHLPYKC DVESDYSYLR IKPHLQEFLS
190 200 210 220 230 240
SVSDFILNYL PPLETNMTHS LQFLHETTKL VYNLPNFTNQ EFQYTKSSAL EQIANCWLIV
250 260 270 280 290 300
LSQDEEKEGN TDVVKVIQEL ELLEKLHEHN EISFNKFEKV VDYCKDKLEQ HELIMNNNEA
310 320
GSGVTSSISD LITVDYSKYS IANTTSI